Infections of the GI System Flashcards

1
Q

What is gastroenteritis?

A

It is the inflammatory process of the stomach or intestinal mucosal surface

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2
Q

Which type of gastroenteritis infection is caused by the pathogen entering the GI tract and multiplying, delay in appearance of symptoms and is accompanied by a fever?

A

Type 1 infection

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3
Q

What is a Type 2 gastroenteritis infection?

A

food poisoning, sudden appearance of symptoms because of the ingestion of the exotoxin, NO fever

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4
Q

Gastroenteritis infections and intoxications cause _ diarrhea

A

acute

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5
Q

What are the characteristics of gastroenteritis?

A

abdominal pain/ cramping, N&V, dehydration, weight loss, fever

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6
Q

What are the 3 clinical syndromes of acute diarrhea?

A

non-inflammatory, inflammatory, and invasive (subset of inflammatory)

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7
Q

Which type of acute diarrhea is most common in north america and is often referred to as “traveler’s diarrhea”?

A

non-inflammatory (secretory)

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8
Q

Which type of diarrhea is caused by viruses such as norovirus, rotavirus and bacteria such as enterotoxigenic E. coli, vibrio cholerae?

A

non-inflammatory (secretory)

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9
Q

Which type of diarrhea is characterized by infection of the small intestine leading to large volumes of watery diarrhea and ABSENCE of fecal leukocytes?

A

secretory

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10
Q

Which type of diarrhea is characterized by an infection in the colon, causing frequent small volume loose stools, with the PRESENCE of fecal leukocytes?

A

inflammatory

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11
Q

Which type of diarrhea has dysentery?

A

inflammatory

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12
Q

What bacteria often causes inflammatory diarrhea?

A

salmonella, shigella and campylobacter jejuni

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13
Q

When vomiting is a dominant symptom what should we consider?

A

viral infection or food poisoning

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14
Q

During the physical exam what 4 things are we looking for that will tell us the severity of the disease?

A
  • orthostatic hypotension
  • tachycardia
  • decreased skin turgor
  • dry mucous membranes
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15
Q

When is it not recommended to do a bacterial culture?

A

if patient has been in the hospital for > 72 hours and has a new onset of symptoms, likely due to C. diff

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16
Q

When are studies for ova and parasites indicated?

A
  • persistent diarrhea (even tho treated with antibiotics)
  • international or wilderness travel
  • day care centers
  • immunosuppression (HIV/AIDS)
17
Q

Which bacteria can molecule assays identify?

A
  • salmonella spp
  • shigella spp
  • campylobacter spp
  • verocytotoxigenic E. coli
18
Q

What medications can also cause diarrhea and must be on the look for?

A
  • metformin
  • colchicine
  • diuretics
  • ACE inhibitors
  • PPIs magnesium containing antacids
  • antibiotics
19
Q

What is the initial focus for management of gastroenteritis?

A

rehydration

20
Q

What are some agents to control diarrhea?

A
  • bulking agents
  • bismuth compounds (prevents water going into stool)
  • antimotility drugs (only in non-inflammatory)
21
Q

What agent that is used to control diarrhea is NOT to be used if person has inflammatory diarrhea?

A

antimotility drugs

22
Q

Which type of therapy is recommended only in severe cases of infectious bacterial gastroenteritis when we do not expect a person to get better on their own?

A

empiric antibiotic therapy

23
Q

what is the prefered method of treatment once positive stool culture or parasite is identified?

A

specific antimicrobial therapy