infections in preg Flashcards
all women in the uk are pregnant are offered what screening tests at 10-12 weeks ……
UTI
HepB
HIV
sphyllis
TORCH infections that cause congenital malformations
Toxoplasmosis
other -VZV or parovirus B19
Rubella
cytomegalovirus
Hs - HIV< hepB , herpes , HPV
tx for toxoplasmosis gondii in a patient who is immunosuppressed on tacrolimus
pyramethamine and sulphadiazine
treat all immunosuppressed pt with toxoplasmosis
reduce risk with spiramycin in the 1st trimester
sx of congenital toxoplasmosis causes
vision loss - chorioretiniits
hydrocephalus
hearing loss
cerebral palsy
intracebral calcification
farmers or around animals
what advice to prevent infection in pregnancy
avoid raw and cured meat or unpasteurised dairy
do not touch/handle pregnant sheep, lambs or cat litter
25w preg women with daughter with chickenpox what do you do for the patient as uncertain if she has had before -
check maternal antibodies
acyclovir should be given if over 20weeks pregnant. If pts is infected less than 20 weeks the risk is low
under 20 weeks immunoglobulins
VZV in preg
low birth weight
skin scarrin g
microcephaly
learning disabilities
2 day neonate. absent fundal reflexes bilaterally and a loud machine murmur on auscultation. sensorineural deafness. Not vaccinated. rash on trunk too
congenital rubella
heart disease, cataracts( bilateral loss of red reflexes) and deafness - triad and also developmental delay
MMR vaccinations given when
1yr , 3yr4months
viral screen carried out and serum PCR shown CMV infection - what is the fetus at risk of developing
hearing loss, visual impairment and learning disability
potters sydnrome - compresed by lack of fluid
pulmonary hypoplasia, flattended nose na dclubbed feet
foetal alcohol sydnome
growth deficiency , smooth philtrum, neurological impairments
sx of CMV congenitally
LBW
rash - blue
microcephaly
enlarged liver and spleen
hearing loss
petechial rash
postnatal testing for CMV
saliva,urine blood
histology shows what with CMV
owl eye cells
