Infections and STDs (2) Flashcards
clinical vignette for vulvovaginitis from bacterial vaginosis
adherent yellowish discharge; pH > 5; fishy amine odor in KOH; clue cells; gram neg dominate
clinical vignette for vulvovaginitis from Candida spp
vulvoaginitis, pruritis; erythema;
discharge w/ consistency of cottage cheese
clinical vignette for vulvovaginitis from Trichomonas vaginalis
“Strawberry cervix”;
foamy purulent discharge;
many PMNs and motile trophozoites micro (corkscrew motility)
Pathogenesis of vulvovaginitis from bacterial vaginosis
overgrowth of Gardnerella vaginalis;
anaerobes
Pathogenesis of vulvovaginitis from candida spp
antibiotic use => overgrowth, immunocompromised
Pathogenesis of vulvovaginitis from trichomonas vaginalis
vaginitis w/ discharge
diagnosis of vulvovaginitis from bacterial vaginosis
clue cells, gram neg rods
diagnosis of vulvovaginitis from candida spp
germ tube test;
gram pos yeasts in vaginal fluids
diagnosis of vulvovaginitis from trichomonas vaginalis
pear-shaped trophozoites w/ corckscrew motility
Case vignette and key clues for PID
adnexal tenderness, bleeding, dyspareunia;
vaginal discharge, fever;
chandelier sign
onset follows menses
pathogenesis for PID caused by Neisseria gonorrhoeae
pili and IgA protease production
pathogenesis for PID caused by chlamydia
intracellular in mucosal epithelia;
TYPE 4 HYPERSENSITIVITY DAMAGE
diagnosis for PID caused by Neisseria gonorrhoeae
Gram neg diplococci in PMNs;
culture on Thayer Martin
diagnosis for PID caused by Chlamydia tachomatis
tissue culture;
intracytoplasmic inclusion bodies in mucosal cells
Case vignette and key clues for Condyloma acuminatum (genital warts)
lesions are papillary/wart-like lesions;
may be sessile or pedunculated;
koilocytotic atypica is present;
anogenital
most common cause for condyloma acuminatum (genital warts)
HPV