Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Infection > Infection 4 Hepatitis > Flashcards

Infection 4 Hepatitis Flashcards

1
Q

what is hepatitis?

A

inflammation of the liver due to cell injury or viruses
can cause collateral liver damage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

describe hepatitis ABCDE

A

A - acute
B - bit of both
C - chronic
D - double trouble (only happens with B)
E - like A

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

transmission of hepatitis ABCDE

A

A - faeco-oral
B - blood, sex, vertical
C - blood, sex
D - blood, sex , vertical
E - faeco-oral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

which hepatitis is chronic?

A

B and C (+D)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

outline the viral structure of hepatitis A

A

ssRNA
positive
nonenveloped
icosahedral
same as E

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

outline the viral structure of hepatitis B

A

dsDNA
enveloped

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

outline the viral structure of hepatitis C

A

ssRNA
positive
enveloped
icosahedral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

outline the viral structure of hepatitis E

A

ssRNA
positive strand
nonenveloped
icosahedral
same as A

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

blood test results of hepatitis patient

A

high bilirubin, ALT + ALP
damage to liver

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what are the different types of jaundice and their causes?

A

Prehepatic - haemolysis
Intrahepatic - hepatitis, drugs, alcohol, cirrhosis
Extraheptic - gall stones, carcinoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

list some liver function tests

A

bilirubin
albumin
alanine transaminase ALT
aspartate aminotransferase AST
alkaline phophatase ALP
coagulation tests INR + PT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

three causes of increased ALT >1000

A

viral hepatitis
drugs
blood clots

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

symptoms of acute hep B

A

jaundice
fatigue
abdominal pain
anorexia
vomiting
arthralgia
ALT/AST >1000

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

outline hep B serology

A
  • HBsAg surface antigen within 6 weeks
  • HBeAg highly infectious e-antigen appears
  • IgM - core antibody appears
  • HBeAb e-antibody appears > less infectious
  • HBsAb surface antibody last to appear > clears virus
  • HBcAg / IgG - persists for life
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what is chronic hep B infection?

A

persistence of HBsAg after 6 months

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

treatment of chronic hep B

A
  • no cure - integrates into host genome
  • lifelong antivirals - suppresses viral replication
17
Q

describe the hep B vaccination

A

consists of genetically engineered surface antigens
3 doses needed
produces a surface antibody response

18
Q

outline whether or not there are HBsAg, HBsAb, HBcAb in acute hep b infection

A

HBsAg +
HBcAb + IgM
HBsAb +/-

19
Q

outline whether or not there are HBsAg, HBsAb, HBcAb in cleared hep b infection

A

HBsAg -
HBcAb + IgG
HBsAb +

20
Q

outline whether or not there are HBsAg, HBsAb, HBcAb in chronic hep b infection

A

HBsAg +
HBcAb + IgG
HBsAb -

21
Q

outline whether or not there are HBsAg, HBsAb, HBcAb in patient who has been vaccinated for Hep B

A

HBsAg -
HBcAb -
HBsAb +

22
Q

who is at risk of hep C transmission

A

IV drug users
sexual contact
infants born to hep C positive mothers
needlestick injury

23
Q

complications of chronic liver disease due to chronic Hep C infection

A

decompensated liver disease
liver cancer
transplant
death

24
Q

symptoms of hep C

A

80% asymptomatic
- fatigue
- anorexia
- nausea
- abdominal pain

25
Q

describe serology test for Hep C

A

anti Hep-C antibody
remains even after clearance

26
Q

what does a positive viral PCR for Hep C confirm?

A

chronic infection

27
Q

treatment for Hep C

A

no vaccine but there is a cure > can get reinfected
antiviral drug combo

28
Q

Who are at risk of hep B transmission/modes of tranmssion?

A
  • vertical
  • sexual transmission
  • IV drug users
  • close household contacts - blood exposure
  • healthcare working via needle stick injuries
29
Q

Patients who had a blood transfusion before what year are at risk of hepatitis C?

A

1991

30
Q

What are the risks of transmission from needle stick injury in:
- HIV
- Hep C
- Hep B

A
  • HIV: 1/300
  • Hep C: 1/30
  • Hep B: 1/3

Infection (16 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions