In-vivo drug mode of action💊

Question 1

cell wall beta lactam
— 1st gen: Gram pos (+)
— 2nd gen: Gram neg (-)
— 3rd gen: Increase against Gram (-)

Answer 1

Cephalosporins

Question 2

— targeting bacterial ribosomes
— They are bacteriostatic

Answer 2

Tetracyclines

Question 3

— Inhibit bacterial protein synthesis. (note: AMINOglycosides = amino acids (protein synthesis)
— Enterobacc

Answer 3

Aminoglycosides

Question 4

— bacteriostatic at lower dose
— bactericidal at HIGHER dose

Answer 4

Macrolides

Question 5

— inhibit DNA synthesis.
— e.g. ciprofloxacin

Answer 5

Fluoroquinolones

Question 6

Folic acid inhibitors

Answer 6

e.g. Sulfinamide, Trimpethotrim

Question 7

distrups phospholipid bilayer

Answer 7

polymixin

Question 8

chloramphenicol mode of action

Answer 8

inhibits microbial protein synthesis