Important Cytokines Flashcards

1
Q

IL-1

A

osteoclast activator

fever and acute inflammation

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2
Q

IL-2

A

stimulates T cells

IL

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3
Q

IL-3

A

simulates bone marrow

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4
Q

IL-4

A

simulates IgE

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5
Q

IL-5

A

Stimulates IgA

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6
Q

IL-6

A

stimulates Acute Phase Protein

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7
Q

IL-8

A

chemotactic for neutrophils

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8
Q

IL-12

A

induces differentiation of t cells into Th1 cells

activates NK cells

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9
Q

TNF-alpha

A

mediates septic shock
vascular leak
WBC recruitment

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10
Q

causes cachexia in chemo patients

A

TNF-alpha

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11
Q

what is secreted by NK cells and T cells in response to IL-12 from macrophages

A

IFN-y

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12
Q

what stemmalates macrophages to kill phagocytksed pathogen and inhibit the differentiation of TH2 cells

A

IFN-y

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13
Q

IL-10

A

reduces inflammation

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