Immunology - Liam Flashcards

1
Q

Only antibody to cross placenta

A

IgG

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2
Q

Type 1 mechanism

A

Antigen reacts wqith IgE bound to mast cells

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3
Q

Type 2 mechanism

A

IgG or IgM binds to antigen on cell surface

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4
Q

Type 3 mechanism

A

Free antigen and antibody (IgG, IgA) combine

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5
Q

Type 4 mechanism

A

T cell mediated

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6
Q

First antibody in response to infection

A

IgM

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7
Q

Most common Ig in body

A

IgA, but alot found on mucosal surfaces so blood levels lower than IgG

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8
Q

IgG function

A

Enhance phagocytosis of bacteria and viruses

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9
Q

Anaphylaxis treatment

A

IM adrenaline

IM hydrocortisone

IV chlorphenamine

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10
Q

What IL induces fever

A

IL1

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11
Q

What activates macrophages

A

Interferon Y

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12
Q

What is compliment system activated by

A

Antigen-antibody complexes (IgM/IgG)

or by polysaccharides (starts at C3)

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13
Q

Ig in breast milk

A

IgA

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14
Q

What T cell mediates antibody immunity

A

Th2 cells

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15
Q

Idiopathic thrombocytopenic purpura is an example of

A

Type 2

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16
Q

SLE is example of

A

Type 3

17
Q

Gene associated with Sjorens syndrome

A

HLA DR3

18
Q

RA example of

A

Type 3

19
Q

What mediates hyperacute organ rejection

A

B cells

20
Q

Gene associated with RA

A

GLA DRB1