Immunology: Extra Immunomodulatory drugs deck

Question 1

Cyclosporine. What is it?

Answer 1

A Calcineurin inhibitor.

(Immunomodulatory drug)

Question 2

Tacrolimus. What is it?

Answer 2

A Calcineurin inhibitor.

(Immunomodulatory drug)

Question 3

Tofacitinib, what is it?

Answer 3

JAK inhibitor, for rheumatoid arthritis.

(Immunomodulatory drug)

Question 4

Apremilast, what is it?

Answer 4

A PDE4 inhibitor, for psoriatic arthritis.

(Immunomodulatory drug)

Question 5

When is rabbit anti-thymocyte globulin used?

Answer 5

Severe allograft rejection

Question 6

Basiliximab, what is it?

Answer 6

-Anti-CD25 for prophylaxis of allograft rejection.

(Immunomodulatory drug)

Question 7

Abatacept, What is it?

Answer 7

CTLA-4 Ig for RA

(Immunomodulatory drug)

Question 8

Rituximab, what is it?

Answer 8

• Anti-CD20 for:
• Lymphoma
• RA
• SLE

Question 9

Natalizumab, what is it?

Answer 9

• Anti-a4-integrin for:
• MS

-Crohn’s disease

Question 10

Tocilizumab, What is it?

Answer 10

• Anti-Il-6R for:
• RA
• Castleman’s disease

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-Castleman’s disease?

Question 11

Infliximab

Answer 11

• anti-TNFa for:
• RA
• Ank spond
• Psoriasis
• IBD

Question 12

Adalimumab, what is it?

Answer 12

• Anti-TNA for:
• RA
• Ank spond
• Psoriasis
• IBD

(Immunomodulatory drug)

Question 13

Certolizumab, what is it?

Answer 13

• Anti-TNA for:
• RA
• Ank spond
• Psoriasis
• IBD

(Immunomodulatory drug)

Question 14

Golimumab, what is it?

Answer 14

• Anti-TNFa for:
• RA
• Ank spond
• Psoriasis
• IBD

(Immunomodulatory drug)

Question 15

Etanercept, What is it?

Answer 15

• TNF-R p75 IgG fusion protein for:
• RA
• Ank spond
• Psoriasis

(Immunomodulatory drug)

Question 16

Ustekinumab, What is it?

Answer 16

-Anti-Il-12 and anti-Il-23 for psoriasis

(Immunomodulatory drug)

Question 17

Denosumab, what is it?

Answer 17

-Anti-RANK-L for osteoporosis

(Immunomodulatory drug)