Immunology and Serology: Parasitic and Fungal Infections Flashcards
causative agent of Toxoplasmosis
Toxoplasma gondii, protozoa
intermediate avidity value in ELISA for IgG avidity
0.20-0.25
IgG with __ avidity indicates more recent infection.
low
More sensitive than detection of IgM antibodies
Detection of anti toxoplasma IgA
infection or disease caused by fungus is called _____.
mycosis
duration of fungal growth
2-4 wks
mushroom poisoning
ex. amanita phalloides, A. verna, A. virosa
Mycetismus
mycotic infection where it produces itchiness and cracking of skin
cutaenous
causative agent of subcutaneous fungal infections
saprophytes
these infections originate in the lungs and disseminate to other locations
systemic
fungi that are commensal in nature
candida albicans
malassezia furfur
main component of fungal cell wall
chitins
CLR that recognizes beta-glucans
dectin 1
recognizes high mannose structures common to fungi
dectin2
may occur in in neutropenic ptx bcs of immunosuppression
Invaive Pulmonary Aspergillosis (IPA)
aspergillus infection affecting external auditory canal
Aspergillus otomycosis
Diagnostic procedure which has increased the ability to diagnose invasive aspergillosis
detection of galactomannan in serum
clearing agent used in direct examination for candida spp. to clearly see hyphae and remove other artifacts
10% KOH
causes pneumonia and septicemia in neutropenic patients
Candida esophagitis
This fungi is saprobe in nature and lives in trees and rotting woods, isolated from pigeons
Candida neoformans
major virulence of C. neoformans
capsule
portal of entry of c. neoformans
Respiratory tract
in direct examination of C. neoformans, what is its characteristic with India ink.
halo around yeast cell
rapid and reliable sero method for cryptococcosis
LA
Histoplasmosis is acquired through inhalataion of
mycelial fragments and microconidia
A titer of ___ in Complement Fixation and Precipitation diagnostic procedure indicates histoplasmosis.
1:32
glycoproteins released by mycelial and yeast-phase cultures in H. capsulatum.
H and M glycoproteins/antigens
presence of H in Precipitin band testing for H. capsulatum indicates
active infection
vector for Coccidiosis immitis.
pigeon
Coccidiosis immitis infection is through inhalation of
arthroconidia spores
