Immunology and Serology Flashcards
Who discovered the vaccine for smallpox using cowpox lesions?
Edward Jenner
Who is the father of immunology that first reported a live attenuated vaccine for rabies?
Louis Pasteur
The study of a host’s reactions when foreign substances are introduced into the body.
Immunology
A branch of immunology that focuses on the laboratory detection and measurement of antigens and antibodies.
Serology
Any foreign substance that
induces an immune response.
Antigen
Protein (Immunoglobulin)
produced by plasma Cells to neutralize antigens that have the primary function to protect against microorganisms
and toxins.
Antibody
An immuno-biological substance designed to produce specific protection against a given disease.
Vaccine
True or False.
Vaccines contain antibodies.
False.
Vaccines contain antigens.
The clumping together of antigen-bearing cells, microorganisms, or particles in the presence of specific antibodies.
Agglutination
What serological procedure refers to the aggregation of test antigens with soluble antibodies to produce visible insoluble complexes?
Precipitation
What serological procedure refers to a midway reaction between agglutination and precipitation?
Flocculation
What is the first step in agglutination where ONE Antibody attaches to the antigenic site (epitope)?
Sensitization
What is the second step in agglutination where sensitized particles adhere to one another forming a “lattice”?
Lattice Formation
What type of agglutination refers to when an antigen is found naturally on the particle?
Direct Agglutination
What type of agglutination refers to when an antigen is first bound to a particle to detect antibodies?
Passive Agglutination
