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comlex > Immunology > Flashcards

Immunology Flashcards

1
Q

Primary lymph drainage site of upper limb and lateral breast

A

Axillary

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2
Q

Primary lymph node drainage site of stomach

A

Celiac

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3
Q

Primary lymph node drainage site of duodenum and jejunum

A

Superior mesenteric

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4
Q

Primary lymph node drainage site of sigmoid colon

A

Colic to inferior mesenteric

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5
Q

Primary lymph node drainage site of rectum

A

Internal iliac

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6
Q

Primary lymph node drainage site of anal canal

A

Superficial inguinal

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7
Q

Primary lymph node drainage site of testes

A

Superficial and deep plexuses to para-aortic

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8
Q

Primary lymph node drainage site of scrotum

A

Superficial inguinal

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9
Q

Primary lymph node drainage site of thigh (superficial)

A

Superficial inguinal

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10
Q

Primary lymph node drainage site of lateral side of dorsum of foot

A

Popliteal

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11
Q

Associated disease with HLA-A3

A

Hemochromatosis

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12
Q

Associated diseases with HLA-B27

A

Psoriasis, Ankylosing spondylitis, inflammatory bowel disease, Reiter’s syndrome

(PAIR)

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13
Q

Associated disease with HLA-B8

A

Graves Disease

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14
Q

Associated disease with HLA-DR2

A

Multiple sclerosis
Hay fever
SLE
Goodpastures

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15
Q

Associated disease with HLA-DR3

A

DM-1

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16
Q

Associated disease with HLA-DR4

17
Q

Associated disease with HLA-DR5

A 
Pernicious Anemia (B12deficiency)
Hashimoto's thyroiditis
18
Q

Associated disease with HLA-DR7

A

Steroid responsive nephrotic syndrome

19
Q

Ig that Fixes complement and crosses placenta

20
Q

Ig that activates eosinophilia

21
Q

Ig that is an antigen receptor on B cell surface

22
Q

Ig that binds mast cells and basophils

23
Q

Ig that fixes complement but does NOT cross the placenta

24
Q

Ig with unclear function

25
Q

Ig produced in the primary (immediate) response to an antigen

26
Q

Ig that is produced in the secondary (delayed) response to antigen

27
Q

Ig that mediates type 1 hypersensitivity

A

IgE

Releases histamine

28
Q

Ig that neutralizes bacterial toxins and viruses

29
Q

Ig that opsonizes bacteria

30
Q

Ig that prevents the attachment of bacteria and viruses to mucous membranes

31
Q

Activates macrophages and Th1 cells

Suppresses Th2

32
Q

Causes fever and acute inflammation, induces chemokine secretion

33
Q

Causes fever and stimulates production of acute phase proteins

34
Q

bruton agammaglobulinemia

A

X-linked recessive disorder, which is caused by a defect in the BTK tyrosine kinase gene, leading to a lack of B cells and inefficient opsonization

35
Q

anti-inflammatory cytokines (2)

A

IL-10, TGF-B

36
Q

Monocyte/Macrophage cell surface marker

37
Q

c-ANCA -antibodies against?

A

autoantibodies against proteinase-3 and are highly specific for Wegener’s granulomatotis

38
Q

p-ANCA- antibodies against?

A

Autoantibodies against myeloperoxidase

comlex (18 decks)

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