Immunology Flashcards
Name a lymphoid organ in which cells of the immune system can be found?
Thymus
Bone marrow
Spleen
What are the principle receptors for the Fc portion of immunoglobulin and the CR1 complement component, respectively?
IgG
C3b
How can T cells be differentiated from B cells?
Secretion of interleukin-2
CD2 marker
Agglutination of sheep erythrocytes
What is the definition of an immunoglobulin?
A protein molecule produced in response to an antigen
Which IgG subclass primarily comprises antibodies to the Rh blood group system?
IgG1
IgG3
IgG-coated red cells will be phagocytized by what effector cells?
monocytes/macrophages
Why is EDTA not conducive to complement activation?
calcium is inactivated
All of the following are factors of antigens that affect the type and extent of immune response except:
genetic locus
Which of the following are produced after exposure to genetically different nonself antigens of the same species?
alloantibodies
What Rh type does a mother have to be to produce antibodies to Rh (D) from an Rh positive infant?
Rh negative
In an immune response, _________ antibodes are formed before ________.
IgM
IgG
All of the following techniques are methods used in the laboratory to detect blood group antigens or antibodies except:
ELISA
At what temperature do IgM antibodies react?
22 degrees celcius
What does the term “zeta potential” mean?
the attraction of negative charges on the surface of red cells to positive charges in an ionic cloud
What is the purpose of the antihuman globulin (AHG) test in blood banking?
it detects red cells coated with antibody by bridging the gap between red cells
