Immunology 3 Flashcards

1
Q

What is the receptor found on a T cell called?

A

It is called the T cell receptor, recognises antibody when bound to MHC

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2
Q

When will a T cell recognise the antibody?

A

When bound to MHC

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3
Q

What are the two types of T cell?

A

CD4+ - Stimulate B cells to produce antibody

CD8+ - Cytotoxic T cells

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4
Q

What are T cells ‘Taught’ during maturation in the thymus?

A

They are taught to recognise own MHC - those that identify it as yours are allowed to live and move on to the next test, after that the T cell isn’t allowed to recognise MHC plus own peptide

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5
Q

When do T cells mature into CD4 + and CD8+ cells?

A

After they have been ‘taught’ to recognise MHC

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6
Q

Where can you find MHC class 1 proteins?

A

Virtually all nucleated cells

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7
Q

What is the function of the MHC class 1 molecule?

A

Presents antigenic peptide, Showi the CD 8+ T cell what is being produced in the cell, triggers a cytotoxic response - releases perforin, releases granzyme B, a protese that enters the cell through the pore and causes apoptosis

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8
Q

Where can you find MHC class 2 proteins?

A

In antigen presenting cells, such as B cells, macrophages and dendritic cells.

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9
Q

What is the function of MHC class 2 receptors?

A

Presents antigenic peptides to CD4 helper T cells which activates macrophages and B cells

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10
Q

Why are T cells said to have memory?

A

They are capable of remembering what has activated them once. Meaning on second exposure they can activate faster and stronger

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