Immunology

Question 1

TH2

Answer 1

Antibody Mediated Immunity
Il-4
Il-5

Question 2

TH1

Answer 2

Cell Mediated Immunity
Activated by IL-12
IL-2 - activates Cd8 T cells
Gamme Interferon - Activates Macrophages

Question 3

IgM

Answer 3

Primary Response
Found on B-Cells
Does not Cross Placenta
Complement

Question 4

CD 4 T Cells

Answer 4

Helper T Cells
Recognize MHC 11
4x2=8

Question 5

CD8 T Cells

Answer 5

Cytotoxic T Cells
Recognize MHC 1
Usually intracellular pathogens (Virus)
8x1=8

Question 6

Il-2

Answer 6

Stimulates T-cells (cd8)

Question 7

Il-12

Answer 7

Stimulates Th1

Question 8

interferon gamma

Answer 8

Stimulates Macrophages/NK cells

Increase MHC expression

Question 9

Neutrophil Opsosinization

Answer 9

IL-8
C5a\
Leukotrien 4b

Question 10

Il-10

Answer 10

Inhibitor of Inflammation

Question 11

IgA

Answer 11

Mucous membrane
prevent bacterial attachment
no complement

Question 12

iL-4

Answer 12

IgE and IgG class switch

Question 13

IL-5

Answer 13

Class switching to IgA

Question 14

Il-3

Answer 14

bone marrow stem cell growth

Question 15

C3a, C4a, C5a

Answer 15

anaphylaxis

Question 16

C3b

Answer 16

opsonization

Question 17

C5b-9

Answer 17

MAC complex

Question 18

Ataxia-telangiectasia

Answer 18

Defect in ATM gene - DNA repair

Ataxia, Angiomas, IgA deficiency

Question 19

Hyper IGM

Answer 19

CD40L problem
cant class switch

Question 20

SCID

Answer 20

IL-2 receptor deficiency

Adenosine Deaminase Deficiency

Question 21

Transplant Rejection

Answer 21

Hyper Acute - Type 2
Acute - Type 2 and Type 4
Chronic -

Question 22

Graft vs Host

Answer 22

Graft T cell reacts against Host

Question 23

Granulatomiss Disease

Answer 23

NADH Oxidase Deficient

Prone to Catalase Bacteria

Question 24

Lymph Nodes

Answer 24

Follicle - B Cells
ParaCortex - T cells
Medulla - plasma cells

Question 25

T-Reg Cells

Answer 25

CD3 | IL-10 and TGF-B

Question 26

IgG

Answer 26

Delayed Response Cross Placenta Complement

Question 27

IgE

Answer 27

Type 1 Hypersensitivy | Eosinophils - Worms

Question 28

Viral Vaccines

Answer 28

Live - Cellular Immunity | Killed - Humoral immunity

Question 29

C1 esterase inhibitor deficiency

Answer 29

Hereditary Angioedema | DONT USE ACE

Question 30

DAF (Gp1 anchored enzyme) deficiency

Answer 30

complement mediate rbc lysis | Paroxysmal nocturnal hemoglobinuria

Question 31

IL-6

Answer 31

Fever and stimulates production of acute phase proteins

Question 32

TNF-alpha

Answer 32

septic shock activates endothelium causes leukocyte recruitment vascular leak

Question 33

Eosinophil Chemotaxis

Answer 33

Histamin

Question 34

Wiskott-Aldrich

Answer 34

``` Was Gene - t cells can't recognize actin cytoskeleton WATER thrombocytopenic purpura eczema recurrent infections ```

Question 35

Chediak-higashi

Answer 35

``` defect in lyososomal trfficiking (LYST) phagosome-lyosome fusion staph/strep infections albinism peripheral neuropathy ```

Question 36

You can Drink Beer at the Bar when your 21

Answer 36

CD-21 B-CELLS RECEPTOR FOR eBv

Question 37

NK cells

Answer 37

cd16 and CD56

Question 38

Live Attenuated Vaccines

Answer 38

``` MMR polio(sabin) influenza(intranasal) varicella yellow fever ```