General Pathology Flashcards

1
Q

Psammoma Bodies

A
Concentric Calcific Spherules
PSaMMoma 
Papillary carcinoma of thyroid
Serous Papillary cystadenocarcinoma of ovary
Meningioma
Malignant mesothelioma
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2
Q

Four Carcinoma Hematogenously Spread

A

Renal Cell Carcinoma
Hepatocellular Carcinoma
Follicular Carcinoma of the Thyroid
Choriocarcinoma

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3
Q

Down Syndrome Cancer

A

We ALL fall DOWN

ALL and AML

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4
Q

PDGF

A

Smooth muscle migration

fibroblast growth

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5
Q

FGF

A

angiognenesis

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6
Q

EGF

A

Cell growth via tyrosine kinase

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7
Q

TGF-beta

A

angiognesis, fibrosis, cell cycle arrest

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8
Q

TGF-alpha

A

permeability
attracts leukocytes
mediates septic shock
inflammation

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9
Q

metalloproteinases

A

tissue remodeling

stimulates myofibroblast

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10
Q

Margination/rolling

A

E/p-selectin on vasculature

sialyl-lewis on leukocyte

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11
Q

Tight-binding

A

ICAm on vasculature

Integrins on leukocytes

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12
Q

P-glycoprotein

A

multi drug resistance protein 1 (MDR1)

cancer cells pump out toxins and drugs

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