immunology Flashcards
what are the layers of the tear film
what are the chemical properties of the eye surface
what immune cells are there in the eye
- macrophages
- neurtophils
- conjuncitval ______ cells
what in the eye has lymphatic drainage
eyelid
-conjunctiva
conjunctiva function in the immune system
- specialised endothelial venules for regulated migration of lymphoid cells
- only place with lymphatic drainage
physical barrier of cornea and sclera
tough collagen coat
what does it mean if a site has immune priviledge
they are able to tolerate the introduction of antigens without elciciting an inflammatory immune response
what sites in the body have immune priviledge
- CNS
- eyes
- testes
- placenta/foetus
what sites in the eye are immune privileged
what are some ocular immune privilege mechanism
- blood tissue barrier and lack of direct lymphatic drainage
- rich in immunosuppressive molecules
what is sympathetic opthalmia
-rare bilateral granulomatous uveitis due to trauma or surgery to one eye
primary mediators of sympathetic opthalmia
T cells
