Immunoglobulin I

Question 0

The light chain consists of these domains:

Answer 0

One variable, one constant domain

Question 1

What allows the immunoglobulins to interact with components of the complement system?

Answer 1

The carbohydrates in the globulin

Question 2

The heavy chain consists of these domains:

Answer 2

One variable, 3-4 constant domains

Question 3

Where does the secretory component of IgA come from?

Answer 3

Mucousal epithelial cells

Question 4

IgD is also known as a _____ receptor.

Answer 4

B cell

Question 5

The structure IgM is different from the structures of other immunoglobulins because it is a…

Answer 5

Pentamer

Question 6

What is the substance holding together the heteromers of IgM and IgA

Answer 6

J chain

Question 7

The heavy chain can come in 5 different kinds, and they are named…

Answer 7

alpha, gamma, delta, epsilon, mu

Question 8

Light chains come in 2 varieties, and they are called…

Answer 8

Lambda and kappa

Question 9

When a cell changes from making IgM to IgA, it can change _____ but it cannot change _____.

Answer 9

Heavy chain (Mu to alpha), light chain (Can’t go lambda to kappa)

Question 10

Which end of the peptide is the variable end of the antibody?

Answer 10

N terminus

Question 11

Is the variable domain present on just the heavy chain, just the light chain, or both?

Answer 11

Both

Question 12

What is the term defining how many epitopes an antibody can bind to?

Answer 12

Valence

Question 13

What are the 10 isotypes of immunuglobulins?

Answer 13

IgG1, IgG2, IgG3, IgG4
IgA1, IgA2
IgM1, IgM2
IgD
IgE

Question 14

The word to express the genetic variability and individuality in antibody structure is called…

Answer 14

Allotype

Question 15

The part of the antibody that makes it unique from all other antibodies is called the…

Answer 15

Idiotype

Question 16

What is the order of antibody prevalence in the body?

Answer 16

G: 1000 mg/dL
A: 200
M: 100
D: 5
E: 0.2

Question 17

Antigen binding to phagocytic cells is mediated by this phagocytic cell surface receptor:

Answer 17

FcR

Question 18

The first component of the complement system to be activated is:

Answer 18

C1q