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General Principles > Immuno Random > Flashcards

Immuno Random Flashcards

1
Q

passive immunity for diseases

A

Tetatnux, Botulinum, HBV, Rabies -> 3 week 1/2 life

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2
Q

live attenuated vaccine examples

A

measles, mumps, rubella, polio (sabin), influenza (intranasal), varicella, yellow ever

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3
Q

inactivated vaccine

A

cholera, hep A, polio, influenza injection, rabies

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4
Q

live vaccine induces

A

cellular response

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5
Q

inactivated vaccine induces

A

humoral response

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6
Q

serum sickness

A

drugs acting as haptins –> fever, uticaria, rthralgia, proteinuria, lymphadenopathy 5-10 days after antigen exposure.

immune complex deposition followed by complement fixation –> tissue damage

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7
Q

arthus reaction

A

subacute antibody-mediated hypersensitivity. antigen-antibody complexes –> complement activation with edema / necrosis

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8
Q

anti-desmoglein antibodies

A

pemphigus vulgarus

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9
Q

anti-glutamate decarboxylase

A

Type I diabetes mellitus

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10
Q

anti-hemidesmosome

A

bullous pemphigoid

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11
Q

antihistone

A

drug-induced lupus

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12
Q

hashimoto thyroiditis

A

antimicrosomal, antithyroglobulin

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13
Q

polymyositis, dermatomyositis autoantibodies

A

anti-Jo1, anti-SRP, anti-Mi-2

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14
Q

primar biliary cirrhosis antibodies

A

antimitochondrial

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15
Q

scleroderma autoantibody

A

anti-Scl70 / anti-DNA topoisomerase I

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16
Q

auto-immune hepatitis autoantibody

A

anti-smooth muscle

17
Q

sjogren syndrome autoantibody

A

anti-SSA, anti-SSB / anti-Ro / anti-La

18
Q

graves autoantibody

A

anti-TSH receptor

19
Q

mixed connective tissue disease autoantibody

A

anti-UI RNP (ribonucleoprotein)

20
Q

granulomatosis w/ polyangiitis

A

c-ANCA / PR3-ANCA

21
Q

celiac diseaes autoantibody

A

IgA antiendomysial, IgA anti-tissue transglutaminase

22
Q

pANCA

A

microscopic polyangiitis / churg-strauss

23
Q

Anti-CCP

A

RA

24
Q

bacterial infections when lacking granulocyte

A

staph, burkholderia cepacia, serratia, nocardia

25
Q

viral infection when lacking B cells

A

enteroviral encephalitis, poliovirus

26
Q

fungal infection when lacking T cell

A

candida / PCP

27
Q

fungal infection when lacking B cells

A

GI giardiasis

28
Q

fungal infection when lacking granulocytes

A

candida / aspergillus

General Principles (16 decks)

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