Immuno Random Flashcards
passive immunity for diseases
Tetatnux, Botulinum, HBV, Rabies -> 3 week 1/2 life
live attenuated vaccine examples
measles, mumps, rubella, polio (sabin), influenza (intranasal), varicella, yellow ever
inactivated vaccine
cholera, hep A, polio, influenza injection, rabies
live vaccine induces
cellular response
inactivated vaccine induces
humoral response
serum sickness
drugs acting as haptins –> fever, uticaria, rthralgia, proteinuria, lymphadenopathy 5-10 days after antigen exposure.
immune complex deposition followed by complement fixation –> tissue damage
arthus reaction
subacute antibody-mediated hypersensitivity. antigen-antibody complexes –> complement activation with edema / necrosis
anti-desmoglein antibodies
pemphigus vulgarus
anti-glutamate decarboxylase
Type I diabetes mellitus
anti-hemidesmosome
bullous pemphigoid
antihistone
drug-induced lupus
hashimoto thyroiditis
antimicrosomal, antithyroglobulin
polymyositis, dermatomyositis autoantibodies
anti-Jo1, anti-SRP, anti-Mi-2
primar biliary cirrhosis antibodies
antimitochondrial
scleroderma autoantibody
anti-Scl70 / anti-DNA topoisomerase I
auto-immune hepatitis autoantibody
anti-smooth muscle
sjogren syndrome autoantibody
anti-SSA, anti-SSB / anti-Ro / anti-La
graves autoantibody
anti-TSH receptor
mixed connective tissue disease autoantibody
anti-UI RNP (ribonucleoprotein)
granulomatosis w/ polyangiitis
c-ANCA / PR3-ANCA
celiac diseaes autoantibody
IgA antiendomysial, IgA anti-tissue transglutaminase
pANCA
microscopic polyangiitis / churg-strauss
Anti-CCP
RA
bacterial infections when lacking granulocyte
staph, burkholderia cepacia, serratia, nocardia
viral infection when lacking B cells
enteroviral encephalitis, poliovirus
fungal infection when lacking T cell
candida / PCP
fungal infection when lacking B cells
GI giardiasis
fungal infection when lacking granulocytes
candida / aspergillus
