Immunity

Question 1

Describe
Role of Immune system

Answer 1

body’s protective response to infection and disease

Question 2

Describe
Innate immunity

Answer 2

Defense system with which you were born

Primary Response: After exposure to antigen, initial production of IgM followed by the production of IgG against the same antigen

Question 3

Describe
Adaptive immunity

Answer 3

occurs after your exposed and you get the antibody

Secondary Response: More rapid production of larger amounts of antibody compared to primary response. IgM may be transiently produced, but IgG is increased making it higher levels

develops over the lifetime of the individual and

provides long-term protection against specific invaders

Question 4

Describe
Hypersensitivity

Answer 4

altered immunologic response to an antigen that results in disease or damage to the individual

Question 5

Identify the risks involved with a patient that is immunosuppressed

Answer 5

Increased chance of infection
Longer healing time

Question 6

Type I, Immunoglobulin E (IgE)–Mediated Reactions

Answer 6

→ First exposure to an allergen leads to antigen processing and presentation of antigen by an antigen-presenting cell (APC) to B lymphocytes, which is under the direction of T-helper 2 (Th2) cells.

→ Then the Th2 cells produce specific cytokines (example: interleukin 4 [IL-4], IL-13, and others) that favor maturation of the B lymphocytes into plasma cells that secrete IgE.

→ Afterwards The IgE is adsorbed to the surface of the mast cell by binding with IgE-specific Fc receptors.

→ When an adequate amount of IgE is bound, the mast cell is sensitized.

→ During a re-exposure, the allergen cross-links the surface bound IgE and causes degranulation of the mast cell. Contents of the mast cell granules, primarily histamine, induce local edema, smooth muscle contraction, mucous secretion, and other characteristics of an acute inflammatory reaction. H1 and H2 receptors, and Antihistamines.

Question 7

Most Common Immunoglobulin

Answer 7

IgG (80-85%)

Question 8

Largest Immunoglobulin

Answer 8

IgM

Question 9

First antibody produced during primary response:

Answer 9

IgM

Question 10

Protects against Infection, after IgM response

Answer 10

IgG

Question 11

immunoglobulin transported across placenta

Answer 11

IgG

Question 12

Secretory Immune System immunoglobulin

Answer 12

IGA

Question 13

Immunoglobulin located in Blood

Answer 13

IgA

Question 14

Immunoglobulin located in Body Secretion

Answer 14

IgA-2

Question 15

Lowest Immunoglobulin concentration in blood

Answer 15

IgD

Question 16

Least concentration in circulation, mediator against allergic reaction

Answer 16

IgE