immune system Flashcards
WHO
World health organization international
CDC
national regulatory agency
disease
alteration of normal tissue
communicable
readily transmitted
pathogenicity
pathogen able to produce a disease “true pathogen”
bacteremia
bacteria in blood
septicemia
infection in blood
Nosocomial infections
are acquired by patients while in health care facilities such as hospitals and clinics. Nosocomial diseases are among some of the most common and costly medical problems today, accounting for ~90,000 deaths annually in the United States alone.
Exogenous nosocomial infections
are the result of pathogens being spread by patients as they are shed from various portals of exit while the patients are in the health care facility.
Endogenous nosocomial infection
are the result of opportunistic pathogens already present in or on the body of the patient and brought on by conditions present at or the direct result of activities at the health care facility.
Iatrogenic nosocomial infections
are spread by health care workers, generally as the result improper sanitary conditions, failure to follow universal precautions, or contaminated invasive surgical or patient care equipment.
Links in the chain of infection
etiological agent-> reservoir (source of microbes)-> portal of exit from resivour-> mode of transmissions (direct or indirect)->portal of entry-> compromised host
course of infection
incubation-> prodromal -> illness -> decline -> convalescence
nonspecific/1st line of defense
skin and intact mucus membranes
nonspecific/2nd line of defense
a local or non specific inflammatory response
stage 1 of inflammatory response
constriction and dilation of blood vessels, leads to hyperemia, bone marrow increases production of WBC
stage 2 of inflammatory response
exudate phase consists of fluids from dead phagocytes, and dead tissue.