Immune response Flashcards
Which lymphocytes are involved in the cell mediated response?
T lymphocytes (mature in thymus gland)
What are antigen presenting cells?
Phagocytes can process antigens and present them on their cell surface membrane.
How do T helper cells become activated?
They have complementary shapes to the antigens that are presented on the phagocytes.
What is it called when T helper cells become activated?
Clonal selection
When T helper cells are activated what happens next?
They are then copied by mitosis
What is it called when T helper cells are copied?
Clonal expansion/clonal proliferation
What 4 things can T helper cells differentiate into?
Killer T cells
Suppressor T cells
Memory T cells
Activated T cells
What do killer T cells do?
They kill pathogens by making pores in pathogen membranes
What do suppressor T cells do?
Inhibits killer T cells and antibody production after the infection is over.
What do memory T cells do?
Remain after the infection is over, can become activated when infected with the same antigen.
What do activated T cells do?
They remain after the infection is over
Which lymphocytes are involved in the humoral response?`
B lymphocytes (mature bone marrow)
How do B lymphocytes become activated?
T helper cells release cytokines, this is clonal selection
Which 2 things can B lymphocytes differentiate into?
Memory B cells
Plasma cells
What do memory B cells do?
Circulate in the blood to respond quickly if the antigen is encountered a second time
Can quickly differentiate into plasma cells
