Immune-Modulating Agents Used in the Treatment of MS

Question 1

Interferon beta-1a (Avonex)

Answer 1

S/E: flu-like symptoms, anemia, depression, development of neutralizing antibodies

Question 2

Interferon beta-1b (Betaseron)

Answer 2

S/E: Injection-site reactions, flu-like symptoms, depression, hematologic/liver abnormalities, development of neutralizing antibodies

Question 3

Interferon beta-1b (Rebif)

Answer 3

S/E: flu-like symptoms, anemia, depression, development of neutralizing antibodies

Question 4

Glatiramer acetate (Capoxone)

Answer 4

S/E: Injection-site reactions, injection-related chest pain, SOB

Question 5

Natalizumab (Tysabri)

Answer 5

PML, hepatotoxicity, hypersensitivity reaction

Question 6

Fingolimod (Gilenya)

Answer 6

Bradycardia, leukopenia