[IEMR14]Hypothalmic-Pituitary Axis Flashcards

1
Q

What are the main functions of oxytocin?(2 points)

A

Contractions of the uterus and ejection of milk from lactating breast

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2
Q

The effects of antidiuretic hormone are inhibited by what electrolytes imbalance/hormone group?(3 points)

A

hypercalcemia, hypokalemia and prostaglandins E

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3
Q

What are the hormones of the anterior pituitary?(7 points)

A

FSH, LH, ACTH, TRH, Prolactin, GH and MSH

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4
Q

What are the hormones of the posterior pituitary gland?(2 points)

A

Oxytocin and Vasopressin

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5
Q
A

Normal Pituitary Gland

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6
Q

What is the most common mass effect of a pituitary adenoma?

A

bitemporal hemianopsia

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7
Q

What are the general clinical/functional disorders of pituitary disorders?

A

increased secretion and decreased secretion

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8
Q

What are the general types of morphological disorders when considering pituitary disorders?(3 points)

A

infalmmatory, necrotic/hemorrhagic, neoplastic

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9
Q

What are the general typesof neoplastic pituitary disorders?(2 points)

A

functional and non-functional

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10
Q

Are most of the neoplastic pituitary disorders benign are malignant?

A

benign

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11
Q

What are the effects of suprasellar expanding masses?(3-5 points)

A

increased intracranial pressure, encroaches on the optic chiasm and may produce bitermporal hemianopsia, its location to the third ventricle, may result in obstructive hydrocephalus, extension into the cavernous sinus could lead to cranial nerve alsy(3,4,5 and , 6) and extention intothe hypothalmus could result in diabetes inpidus

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12
Q

What percentage of the pituitary gland must be destroyed to produce complete hypopituitaryism?

A

75% must be destroyed

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13
Q

In adults, hypopituitarism is most commonly due to what pituitary disorders?(3-6 points)

A

nonfuncitoing pituitary adenoma, Sheehan syndrome, ischemic injury, empty sella syndrome, radiation and surgery

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14
Q

What is the most common cause of hypopituitarism in children?

A

craniopharyngiomas

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15
Q

What are the types of hypothalmic lesions that cause hypopituitaryism?(3 points)

A

Tumors, inflammatory and genetic diseases

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16
Q

What are the general types of hypothalmic tumors that cause hypopituitaryism?(2 points)

A

benign and malignant

17
Q

What are the types of maliganant tumors that cause hypopituitaryism?(2 points)

A

carcinoma of the lung and carcinoma of the breast

18
Q

What are the types of inflammatory hypothalmic lesions that lead to hypopituitaryism?

A

sarcoidosis and tuberculous meningitis

19
Q
A

Sarcoidosis

20
Q

What is the sequence of hormone deficiency with the pituitary gland?

A

GGTAP: Gonadotropin, Growth hormone, thryoid stimulating hormone, adrenocorticotropic hormone and prolactin

21
Q
A