Hypothalamic Tumors Flashcards
What are the two most common tumors of the hypothalamus causing problems in the pituitary gland?
Gliomas and craniopharyngiomas
What are the two age groups of patients presenting with cranios?
5-15 and 65 years and older.
What is the most common clinical sign of children who have a cranio?
Growth retardation because of hypo function of pituitary
Two most common presenting symptoms of patients with cranios overall?
Headaches and visual problems
What is the most common gene mutation for cranios?
B catenin of the WNT pathway
2 characteristic features of cranios if you physically look at the brain with the tumor?
Cystic and multiloculated
Two places these cranios typically invade?
Optic chiasm and third ventricle
What do they think the cranios derive from?
Rathkes pouch
What type of epithelium are cranios?
Squamous
What is a key diagnostic feature of cranios?
Wet keratin
What is the major difference in the histo of cranios in kids and adults?
Adults is papillary
