Diabetes Part 3

Question 1

2 histo features of type 1 diabetes?

Answer 1

Reduction in the number and size of islets

T cell infiltrate

Question 2

What is the hallmark of diabetic macrovascular disease on histo?

Answer 2

Accelerated atherosclerosis of the aorta and large and medium arteries.

Question 3

What is the histo hallmark for the vascular lesion associated with HTN that can be associated with diabetic patients?

Answer 3

Hyaline arteriosclerosis

Question 4

One of the most consistent morph features of diabetes in blood vessels is what?

Answer 4

Diffuse thickening of the basement membrane.

Question 5

What are the 3 lesions encountered in the kidney because of diabetes?

Answer 5

Glomerular lesions, renal vascular lesions, pyelonephritis.

Question 6

What are the 3 most important glomerular lesions because of diabetes?

Answer 6

Capillary basement membrane thickening, diffuse mesangial sclerosis and nodular glomerular sclerosis

Question 7

What is another name for nodular glomeruloscelosis?

Answer 7

Kimmelsteel Wilson disease.

Question 8

What is the gold standard for urine albumin tests?

Answer 8

UA:CR ratio

Question 9

3 complications in the eye due to diabetes?

Answer 9

Too much Neovascualrization due to hypoxia
Cataracts
Glaucoma

Question 10

What are the three most common causes of death in chronic diabetes?

Answer 10

MI, renal failure and stroke

Question 11

4 types of infections diabetics are susceptible to?

Answer 11

Skin, TB, pneumonia and pyelonephritis