hyperthyroidism Flashcards
hyperthyroidism
overproduction of thyroid hormone by thyroid gland
thyrotoxicosis
an abnormal and excessive quantity of thyroid hormone in body
primary hyperthyroidism
due to thyroid pathology
secondary hyperthyroidism
thyroid is producing excessive thyroid hormone as result of overstimulation by TSH
Grave’s disease
autoimmune condition where TSH receptor antibodies cause primary hyperthyroidism
most common cause hyperthyroidism
TSH receptor antibodies
mimic TSH and stimulate TSH receptors on thyroid gland
toxic multinodular goitre
nodules develop on thyroid gland and act independantly of normal feedback system
continuously produce excessive TH
exopthalmos
bulging of eyeball out socket
due to inflammation and hypertrophy of tissue behind eyeball
causes of hyperthyroidism
grave’s
toxic multinodular goitre
solitary toxic thyroid nodule
thyroditis
features of hyperthyroidism
anxiety + irritability sweating heat intolerance tachycardia weight loss fatigue freq loose stools sexual dysfunction
unique features of grave’s disease
diffuse goitre (without nodules)
eye disease
bilateral exopthalmos
pretibial myxoedema
unique features of toxic multinodular goitre
goitre with firm nodules
most pt > 50 yrs
DeQuervain’s thyroiditis
viral infection
hyperthyroid phase followed by hypothyroid phase
DeQuervain’s thyroiditis presentation
fever neck pain tenderness dysphagia hyperthyroid features
DeQuervain’s thyroiditis Mx
self limiting condition
NSAIDs for pain
Beta blocker for symptomatic releirf
