misc

Question 1

bendroflumethiazide - effect on blood sugars

Answer 1

can increase blood sugars

Question 2

medications causing hyopthyroidism

Answer 2

lithium
amiodarone
anti-thyroid drugs e.g. carbimazole

Question 3

amiodarone effect on thyroid

Answer 3

can cause hypothyroid (more common) or hyperthyroid

Question 4

Mx of DKA - what to do about pt normal insulin regime

Answer 4

long acting insulin should be continued but short acting insulin should be stopped

Question 5

Nelson’s syndrome

Answer 5

occurs after bilateral adrenelectomy due to Cushing’s syndrome

increased CTRH –> inc stimulation ant pituitary –> enlarged pituitary –> pituitary adenoma

results in headache, visual field defects, hormonal issue

Question 6

Nelson’s syndrome Mx

Answer 6

transphenoidal surgery

Question 7

calculating insulin regime

Answer 7

24hr requirement = 0.5units x weight

50% basal (long acting insulin)
50% bolus (rapid, split between 3 meals)

Question 8

PTH and PTHrP levels in hypercalcamia secondary to malignancy

Answer 8

PTH low

PTHrP high

Question 9

diagnosing acromegaly

Answer 9

1. Serum IfF

2. OGTT to confirm

Question 10

waterhouse friderichsens syndrome

Answer 10

adrenal haemorrhage –> adrenal failure

Question 11

Ix primary hyperaldosteronism

Answer 11

1. plasma aldosterone renin ration
2. CT
3. adrenal venous sampling

Question 12

pituitary apoplexy

Answer 12

bleeding into pituitary gland

occurs in pt with pituitary tumour