Hypersensitivity summary table Flashcards
What is hypersensitivity ?
Excessive undesirable reactions produced by the normal immune system.
How many classes are there for hypersensitivity reactions?
4
What is another name for type 1 reactions?
Allergic reactions.
What are the two types of reactions for type 2 hypersensitivity reactions?
Cytotoxic and no cytotoxic.
What is another name for type 3 reactions?
Immune complex reactions.
What is another name for type 4 reactions?
Cell mediated/ delayed- type hypersensitivity.
What three classes of hypersensitivity reactions involve infectious diseases?
Types 2,3 and 4.
Examples of Type 1 hypersensitivity.
Hay fever, anaphylaxis to drugs, SOME food allergies, SOME asthma, allergy to animals and animal products.
Examples do type 2 (non cytotoxic) are:
Myasthenia Gravis, Grave’s Disease.
Examples of type 2 (cytotoxic) hypersensitivity are:
Good-pasture’s Disease, rheumatic fever, hemolytic disease of newborns, Autoimmune or drug-induced hemolytic anemia.
Examples of type 3 hypersensitivity reactions are:
SLE, RA, glomerulonephritis, serum sickness (anti venoms).
If a bacterium is catalase +, what does it form?
Forms granulomas
Examples of type 4 hypersensitivity reactions are:
Tuberculin test, Poison Ivy, leprosy, Hashimoto’s thyroiditis, graft versus host disease.
Staph aureus is….?
Is a cocci, catalase +, coagulase +, gram +
What is beta and alpha-hemolysis?
Beta-hemolysis is complete hemolysis whereas alpha-hemolysis is partial hemolysis
In staph epidermidis and saprophyticus, is there any hemolysis?
no
What contributes to fast onset of food-poisoning?
Staph aureus and bacillus cereus
Type I hypersensitivity is immediate hypersensitivity mediated by?
IgE mediated and complement has no roles
Gram + optochin resistant bacteria?
viridans
Type II is mediated via and leads to?
Mediated via cytotoxicity and leads to rheumatic fever
Type III is mediated via and leads to?
Mediated via immune complex and leads to glomerulonephritis
Type IV is what kind of hypersensitivity and give some examples?
It is delayed hypersensitivity and examples include tuberculin test, leprosy and posion ivy
Three bacterias that have IgA (found in breastmilk and other bodily fluids) are?
Nerisseria, hemophileus, strep pneumo
What are the 5 types of immunoglobulins?
MADGE or GAMED: IgM, IgA, IgD, IgG, IgE
