Hypersensitivity

Question 1

What is hypersensitivity?

Answer 1

The antigen specific immune responses that are either inappropriate or excessive and result in harm to host

Question 2

What types of triggers are there?

Answer 2

Exogenous

Intrinsic

Question 3

What are some exogenous triggers?

Answer 3

Non-infectious substances
Infectious microbes
Drugs

Question 4

What are some intrinsic triggers?

Answer 4

Infectious microbes

Self-antigens

Question 5

How many types of hypersensitivity are there?

Answer 5

4

Question 6

What is type 1 hypersensitivity?

Answer 6

Immediate (allergy)

Question 7

What is type 2 hypersensitivity?

Answer 7

Antibody mediated

Question 8

What is type 3 hypersensitivity?

Answer 8

Immune complex mediated

Question 9

What is type 4 hypersensitivity?

Answer 9

Cell mediated (delayed)

Question 10

What are the phases of hypersensitivity reactions?

Answer 10

Sensitization phase

Effector phase

Question 11

What is the sensitization phase?

Answer 11

First encounter with antigen

Activation of APCs and memory effector cells

Question 12

What is the effector phase?

Answer 12

Pathological reaction upon re-exposure

Activation of memory cells of adaptive immunity