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Immune System > Food Allergy > Flashcards

Food Allergy Flashcards

1
Q

What is allergy?

A

A hypersensitivity reaction initiated by specific immunological mechanisms - can be IgE mediated or non-IgE mediated

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2
Q

What is an allergen?

A

Any substance stimulating the production of IgE or a cellular immune response

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3
Q

What is sensitivity?

A

Normal response to a stimulus

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4
Q

What is hypersensitivity?

A

Abnormally strong response to a stimulus

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5
Q

What is sensitisation?

A

Production of IgE antibodies after repeated exposure to an allergen

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6
Q

What is atopy?

A

A tendency to produce IgE antibodies in response to ordinary exposure to potential allergens

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7
Q

What is anaphylaxis?

A

A serious allergic reaction with bronchial, laryngeal and cardiovascular involvement that is rapid in onset

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8
Q

What are major food allergens?

A 
Gluten 
Crustaceans
Eggs
Milk 
Nuts
Peanuts
Soya
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9
Q

How can food allergy presentation be split?

A

IgE mediated

Non-IgE mediated

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10
Q

What is the symptom onset in IgE mediated?

A

Immediate - 5-30 mins

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11
Q

What is the symptom onset in non-IgE mediated?

A

Delayed - hours-days

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12
Q

What are the common foods that trigger IgE mediated?

A

Milk + eggs
Peanuts
Tree nuts
Fish + shellfish

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13
Q

What are the common foods that trigger non-IgE mediated?

A

Milk
Soya
Wheat

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14
Q

What are the symptoms of IgE mediated?

A

Pruritus
Urticaria
Angioedema
Wheeze

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15
Q

What are the symptoms of non-IgE mediated?

A 
Eczema 
Abdo pain 
GORD
Constipation 
Loose stools
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16
Q

How can non-IgE mediated present?

A

Proctocolitis
Enterocolitis
Esoinophilic oesophagitis

17
Q

What is proctocolitis?

A

Passage of red blood in mucousy stools in otherwise asymptomatic infants

18
Q

What is enterocolitis?

A

Multiple and varying GI symptoms

19
Q

What is eosinophilic oesophagitis?

A

Symptoms from oesophageal inflammation and scarring of feeding disorders

20
Q

How can food allergy be diagnosed?

A

Skin prick test

Immunoassays

Immune System (9 decks)

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