Hypersensitivity Flashcards
1
Q
Type 1 hypersensitivity
A
Anaphylaxis
IgE
Asthma, allergy, Hayfever
2
Q
Type II
A
Cell Bound
IgG or IgM
- Autoimmune haemolytic anaemia
- ITP
- Goodpasture’s syndrome
- Pernicious anaemia
- Acute haemolytic transfusion reactions
- Rheumatic fever
- Pemphigus vulgaris / bullous pemphigoid
3
Q
Type III
A
IgG, IgA
Free antigen and antibody
* Serum sickness
* Systemic lupus erythematosus
* Post-streptococcal glomerulonephritis
* Extrinsic allergic alveolitis (especially acute phase)
4
Q
Type IV
A
T cell mediated
- Tuberculosis / tuberculin skin reaction
- Graft versus host disease
- Allergic contact dermatitis
- Scabies
- Extrinsic allergic alveolitis (especially chronic phase)
- Multiple sclerosis
- Guillain-Barre syndrome
5
Q
Type V
A
Graves / Myasthenia
6
Q
A