hyperplasia and hypertrophy of cardiomyocytes

Question 1

physiological cardiac hypertrophy

Answer 1

response to exercise or pregnancy

reversible

Question 2

physiological hypertrophy is caused by

Answer 2

• organized growth of cardiomyocytes
• new sarcomers within the myofibrils (increased thickness)
• proportional changes in ventricular volume and wall thickness
• enlarged cardiomyocytes supported by collogen fibers outside the sarcolemma

Question 3

pathological cardiac hypertrophy

Answer 3

responds to chronic stress

Question 4

response to chronic stress due to

Answer 4

1. increased preload in ventricle

2. increased afterload in ventricle

Question 5

increased preload in ventricle

Answer 5

think stretch

-increased EDV

Question 6

increased after load in the ventricle

Answer 6

think pressure

-often caused by increases in ESV

Question 7

pathological hypertrophy leads to a _____ in stroke volume

Answer 7

decrease

Question 8

results in a disorganized, fibrotic increase in cardiomyocyte size yet a decrease in ventricular effectiveness due to stiffness

Answer 8

pathological hypertrophy