Hyperlipidemia drugs Flashcards
Never take Statins and
Fibrates together, myopathy
Never take this with Statins, will cause toxicity
grapefruit juice
Potentiates coumadin
Lovastatin, simvastatin
suffix monoclonal ABs against PCSK9
-ocumab
use if family hx hypercholesteremia, & ASCVD risk
Bile acid binding resins
SE: GI upset
bine acid binding resins
activates PPAR, reduces TAGs by 50% and increases HDL
Fibrates
CI gallbladder disease
fibrates
hyperTAG
fibrates
potentiates coumadin, indaneiodine
fibrates
inhibits AAC, inhibits sx of fatty acids
niacin
familial hyperlipoproteinemia and LOW HDL
combo therapy Niacin w/ Statin
SE include: flushing, pruritis (cutaneous vasodilation)
Niacin
Contraindicated peptic ulcers
Niacin
SEVERE hyperTAG
Omega
Neurocognitive SE
PCSK9 inhibitors
Hyperglycemia, hyperuricemia
Niacin
decreased mortality in CAD
Statins