Hemantinics Flashcards

1
Q

Oral Iron

A

Ferrous Sulfate

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2
Q

Iron deficiency, normal GI absorption

A

Ferrous Sulfate

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3
Q

Can cause ACUTE IRON toxicity in children

A

Ferrous Sulfate

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4
Q

IV Iron

A

Ferric Salts/Dextra

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5
Q

Iron deficiency, GI absorption limited

A

Iron Dextran

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6
Q

Chronic Renal Disease

A

Iron Dextran

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7
Q

Extensive CHRONIC anemia

A

Iron Dextran

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8
Q

SE: rush, fever, phlebitis, arthralgia, bronchospasm, neuro, GI, urticaria, death

A

Iron Dextran

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9
Q

need this w/ Vitamin B12

A

-balamin!

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10
Q

Pernicious Anemia USE

A

Vitamin B12

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11
Q

difference between Folate and Vitamin B12?

A

B12 will correct neuro abnormalities!

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12
Q

Do not use in pernicious anemia/intrinsic factor deficiency

A

Folate!

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13
Q

Acute iron toxicity in kids, use

A

Deferoxamine (Iron chelator)

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14
Q

SE: bloody diarrhea, necrotizing gastroenteritis

A

Deferoxamine!

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15
Q

SE: HTN, thrombosis

A

EPO, darbeoietin Alfa

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16
Q

Renal Failure

A

EPO, dPO alfa

17
Q

bone marrow cancer, AIDS/HIV

A

EPO, dPO alfa

18
Q

Filgrastim

A

Myeloid GF

19
Q

Sargramostim (GM-CSF)

A

Myeloid GF

20
Q

tx: NEUTROPENIA, Aplastic anemia

A

Filgrastim, Sargramostim

21
Q

SE: bone pain, fever, malaise, arthralgia, myalgias

A

Filgrastim, Sargramostim

22
Q

Megakaryocyte GF

A

Oprelvekin (IL-11)

23
Q

Tx: THROMBOCYTOPENIA, platelet tx, non-myeloid cancers

A

Oprelvekin

24
Q

SE: headache, dizziness, dyspnea

A

Oprelvekin

25
Q

Microcytic anemia

A

Iron Deficiency

26
Q

Macrocytic anemia

A

Folic acid deficiency

27
Q

Highest sources of dietary iron

A
  1. cereal
  2. oysters
  3. chocolate
  4. beef liver
  5. lentils
28
Q

non-heme iron has…

A

less bioavailability

29
Q

polyphenols (teas, coffee)

A

decrease iron bioavailability

30
Q

Iron therapy is CI:

A

HEMOLYTIC anemia

31
Q

Necrot. gastroenteritis, vomiting, ab. pain!, bloody diarrhea, shock, lethargy, dyspnea, severe metabolic acidosis

A

Acute Iron Toxicity

32
Q

MEGALOBLASTIC anemia

A

Vitamin B12 deficiency

33
Q

Vitamin B12 is produced by

A

bacteria!

34
Q

Sources of Folic Acid

A

Yeast, liver, kidney, green veggies

35
Q

G-CSF helps to

A

differentiate neutrophils

36
Q

GM-CSF helps

A

granulocytic, erythroid, megakaryocyte, neutrophil, t-cell lines and inflammation