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Pharm > Antiepileptics > Flashcards

Antiepileptics Flashcards

1
Q

Phenytoin MOA

A

Na+

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2
Q

Lamotrigine, Felbamate MOA

A

Na+ and Glutamate

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3
Q

Ethosuximide

A

Ca+

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4
Q

Gabapentin

A

Na+, GABA, Ca+

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5
Q

Nystagmus

A

Phenytoin

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6
Q

Gingival Hyperplasia

A

Phenytoin

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7
Q

Rash/SJS

A

Lamotrigine

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8
Q

Spina Bifida Tetrogen

A

Valproate

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9
Q

Aplastic anemia, hepatoxicity

A

Felbamate

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10
Q

Binds to SV2A

A

Lamotrigine

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11
Q

Absence seizures

A

Ethosuximide

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12
Q

Eliminated by kidneys, PN

A

Gabapentin

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13
Q

Tx DM PN

A

Pregabalin

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14
Q

Migraine Headache tx

A

Topiramate

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15
Q

Possible Retinal Neuropathy

A

Vigabatrin

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16
Q

Acute seizures

A

Diazepam

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17
Q

leukopenia, hyponatremia

A

carbamazepine

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18
Q

trigeminal neuralgia

A

carbamazepine

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19
Q

bipolar disorder

A

carbamazepine

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20
Q

decrease in bone mineral content

A

phenytoin

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21
Q

Focal seizure tx

A

Carbamazepine, Lamotrigine, Leviracetam

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22
Q

General, Absent

A

Valproate, Ethosuximide

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23
Q

General, Tonic Clonic or Unknown

24
Q

Zero order kinetics

25
Q

Status Epilepticus (acute seizures)

A

Diazepam or Lorazepam

26
Q

High Potency Typical

A

Play Halo while high and get the Flu
Haloperidol
Fluphenazine

27
Q

MOA: Induce EPS, block D2 receptors, increase prolactin

A

Haloperidol, Fluphenazine (high), Chlorpromazine (low)

28
Q

Tx Schizophrenia

A

Haloperidol, Fluphenazine

29
Q

More sedative, CNS effect in

A

Low potency

30
Q

Low Potency Typical antipsychotics

A

Chlorpromazine

31
Q

risk weight gain, DM, hyperlipidemia

A

Atypical antipsychotics

32
Q

Major depression tx

A

ARipiprazole

33
Q

ARipiprazole + Clozapine MOA:

A

Block 5-HT

34
Q

Clozapine SE

A

agranulocytosis, need weekly WBC checks

35
Q

Atypical Antipsychotics Mnemonic

A

Psychoas ARe ZAPped and DONE

ARipiprazole, cloZAPine, olanZAPine, risperiDONE

36
Q

autism

A

risperidone

37
Q

anterograde amnesia

38
Q

Insomnia tx

A

Flu, Tema… Pam takes Tema-flu for insomnia

39
Q

potentiate GABA inhibition

A

benzodiazepams!

40
Q

BZD receptor agonist

A

Zolpidem/Ambien

41
Q

Stimulates benzo receptor

A

Zolpidem/Ambien

42
Q

BZD/Rescue Antagonist

A

Flumazenil

43
Q

Partial agonist 5HT-1A receptor

44
Q

Antianxiety, good for truck drivers and workers with high risk jobs need to be awake

45
Q

Short acting

46
Q

TRIcyclic antidepressants mnemonic

A

“depressed cause I TRIed but I TRIPT at PRAM”

  • itri
  • tript
  • ipram
47
Q

SE: orthostatic hypotension, sexual dysfunction, sedation, weight gain

A

tricyclic antidepressants

48
Q

Quinidine-like effects

A

tricyclic antidepressants

49
Q

mild stimulant + antidepressant

A

BUPROPRION

50
Q

SSRI’s suffix

51
Q

SSRI mnemonic

A 
"SSRy SER, the PARrot FLUw into the CITy"
SERtraline
PARoxetine
FLUoxetine
CITalopram
52
Q

SSRI MOA:

A

inhibits UPTAKE of 5-HT

53
Q

SE: suicidality

54
Q

eat food containing TYRAMINE… HTN crisis

55
Q

MAOIs mnemonic

A

“SEL MAyO w/ PHENEL”
SELegiline
PHENELzine

56
Q

hand tremor

57
Q

Lithium mnemonic

A

“battery powered VLC”
Valproic Acid
Lamotrigine
Carbamazepine

Pharm (12 decks)

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