Hydroxocobalamin Flashcards
1
Q
Brand Name
A
Cyanokit
2
Q
Drug Class
A
Antidote
3
Q
Mechanism of Action
A
Binds directly to cyanide, forming cyanocobalmin (Vitamin B12) which is readily secreted
4
Q
Indications
A
Known or suspected cyanide poisoning
5
Q
Contraindications
A
None in emergency setting
6
Q
Adverse Effects
A
Hypertension, allergic reactions have been reported, N/V, Dyspnea, Indigestion, Dizziness, Bright red skin pigmentation that can last for several days
7
Q
Precautions
A
Not compatible in same IV with many other medications
8
Q
Dose
A
5g IV infusion at 15 ml/min over 15 mins.
May repeat x1
Pedi: 70mg/kg at 15 ml/min over 15 mins.
