human physiology Flashcards
respiration following steps
- atmospheric air in , alveolar air out
- diffusion of o2 co2 across alveolar membrane
- transport of gases by blood
- diffusion of o2 and co2 btw blood and tissue
- utilisation of o2 and co2 out
tracheal tubes
insects
Respiratory organ
skin or moist cuticle, cutaneous respiration
earthworm and frog
common passage for food and air
pharynx
healthy human breaths
12-16 times per minute
3 layer of respiratory membrane
alveolar epithelium
basement membrane
endothelium
association
more po2
less co2,temp,H+
shift to left
whose solubility is more co2 or o2
co2 is 20-25 times more soluble than o2
normal condition every 100 ml deliver ——- o2 to tissue
5ml
every 100 ml o0f deoxygenated blood —— ml of co2 to alveoli
4
respiratory rhythm centre , location and functions.
medulla oblongata
chemosensitive area
adjacent to rhythm centre
pnemotaxic centre
pons
asthma
inflammation of bronchi and bronchioles, wheezing
emphysema
smoking, chronic disorder
3 major proteins in plasma
fibrinogen - clotting of blood
globulin - defence mechanism
albumin- osmotic balance
Occupational respiratory disorder
inflammation of fibriosis
plasma 55%
90-92% water in plasma
6-8% proteins
Leucocyte
granulocyte -
neutrophil- 60-65% phagocyte
Eosinophils - 2-3% resist infections , suppress
allergic reactions
Basophil -0.5-1% secrete histamin, serotonin, heparin
Agranulocyte-
lymphocyte 20-25%
monocyte 6-8% phagocytosis
formed elements 45%
Thrombocytes
Leucocyte- 6000-8000 mm^-3, nucleated
Erythrocytes - 5-5.5 million mm^-3, enucleated
serum
plasma - clotting protein
platelets
150000-350000 mm^-3
blood group , antigen , antibody
A - A - ANTI B
B - B - ANTI A
AB - A,B - NIL
O - NIL - ANTI A,B
universal donor
O-
universal recipients
AB+
RH incompatibility / haemolytic disease of new born/ erythroblastosis foetalis
mother rh -ve
child rh +ve
first pregnancy - anti RH antibody formed
second pregnancy- antibody cross the placenta, RCB ruptures death of foetus or mother can happen, anaemia , jaundice
Prothrombin to thrombin converting enzymes
thrombokinase
Fibrinogen to fibrin converting enzyme
thrombin
closed circulatory system,
annelids , chordates
2 chambered
fish , single circulation
3 chambered heart
reptiles, amphibians except crocodile
sino atrial node
natural pace maker
70-75 min^-1
initiate and maintain rhythmic activity
atrio ventricular node
pace setter
bundle of his
AV bundle + purkinjee fibre
time in which 1 cardiac cycle takes place
0.8 sec
systol, diastole
contraction, relaxation
cardiac output
stroke volume * heart rate
70ml/ beat. * 75beat/ min
= 5.25L/ min