Human Papilloma Virus (HPV) Flashcards
1
Q
HPV
Properties
A
DsDNA
Naked Virus
2
Q
1-4
A
Cutaneous Common Warts = Verruca Vulgaris
3
Q
6-11
A
Recurrent Respiratory Papillomatosis [RRP]
/Laryngeal Papillomatosis
Anogenital Warts: Condyloma Accuminata
4
Q
16-18
31-33 causes same thing.
A
Anogenital Cancers
cervical, anal, vaginal, vulvular.
Causes Squamous Cell Carcinoma.
5
Q
Vaccine
A
Guardasil (4,6,16,18)
6
Q
Pathogensis
A
HPV has been to produce E7 which degrades p53, E6 degrades Rb. These proteins are anti-cancer. They won’t allow G1/S transition. Cancer develops.
Colonic Cancer. Post-Sexual bleeding.
Dx: Squamous cell will become - Koilocytes: highly dense nucleus filled structures.
It’s common ijn AIDS patient.
