HSV-1/HSV-II

Question 1

Properties

Answer 1

dsDNA
Enveloped
TORCHeS
Replicates within-Nucleus
Linear dsDNA
CowDry Bodies: Intranuclear inclusion are formed. (Highly eosinophilic and are made of protein+nucleic acids)

Lives in Trigemminal Ganglia.

Question 2

Transmission

Answer 2

Saliva, Sexual, Perinatal.

Question 3

HSV-1

Answer 3

1. GingivoStomatis
2. Cold-Sores (Labial Herpes)
3. KeratoConjunctivities.
   (Flourescein Light Lamp: Snake like ulcers).
4. Temporal Lobe Encephalitis (Confusion, bizzare behavior, altered mental status).
5. Most common cause of Sporadic Encephalitis.
6. Dew-Drops on Rose Petal Lesions.
7. Herpetic Whitlow
8. Erythema Multiform lesions on hands and feet.

Question 4

HSV-II

Answer 4

Resides in: Sacral Ganglia.
Painful blisters on Genitals, Lymphadenopathy.
Causes Aseptic Meningitis.

Question 5

Diagnosis
Tx

Answer 5

1. Tzanck - Multinuclear Giant cells.

Acyclovir.