Hubbard RBCs

Question 1

if you had one test to work up anemia what would it be

Answer 1

reticulocyte count

Question 2

hallmark disease for stem cell proliferation defect

Answer 2

aplastic anemia

Question 3

what is aplastic anemia characterized by

Answer 3

hematopoietic cells, fatty replacement of marrow, and pancytopenia

Question 4

causes of aplastic anemia

Answer 4

• infection (vrial hepatitis, EBV, Parvovirus, HIV)
• Radiation
• Drugs (chloramphenicol and quinacrine)
• toluene
• glue

Question 5

Acanthocytes on peripheral smear

Answer 5

chronic kidney disease . . need creatinine clearance to be 30 or less

Question 6

MCV MCHC of chronic kidney disease

Answer 6

normochromic normocytic

Question 7

Factitious anemia due to autophlebotomy

Answer 7

Lasthenie de Ferjol syndrome

Question 8

what is the gene that can have altered expression in acquired malabsorption iron deficiency anemia

Answer 8

nRAMP2 gene which codes for DCT1 (DMT1) that helps with Fe 2+ absorption

Question 9

TIBC in iron deficiency anemia

Answer 9

increased

Question 10

normal reticulocyte count

Answer 10

.5-1.5

Question 11

ice cravings in iron deficiency anemia

Answer 11

pagophagia

Question 12

what foods and drugs can induce hemolysis with anemia in G6PD deficiency

Answer 12

• Fava Beans

- sulfa containing meds

Question 13

retic. count in anemia of enzyme deficiency

Answer 13

elevated

Question 14

Lab features of hemolysis

Answer 14

• decreased haptoglobin
• increased LDH and bilirubin
• urine hemosiderin may be elevated in some
• plasma hemoglobin may be elevated if severe

Question 15

most common cause of hemolytic anemia in the world

Answer 15

malaria

Question 16

“blackwater fever”

Answer 16

malaria

Question 17

Oroya fever

Answer 17

Bartonellosis . . sand flea

Question 18

“maltese cross”

Answer 18

Babesiosis