HPV-Related Cancers - part II Flashcards
etiology of oral squamous cell carcinoma (OSCC)
- smoking
2. ETOH
etiology of oropharyngeal squamous cell carcinoma (OPSCC)
increased number of sexual partners, majority HPV+
what percent of people with oropharyngeal squamous cell carcinoma (OPSCC) has HPV 16?
90%
primary clinical features of oral squamous cell carcinoma (OSCC)
- leukoplakia
- erythroleukoplakia
- erythroplakia
- ulcer
primary clinical features of oropharyngeal squamous cell carcinoma (OPSCC)
- enlarged lymph node in neck
- dysphagia
- very subtle, asymptomatic initially
T/F: incidence of oral squamous cell carcinoma (OSCC) is increasing
false, decreasing
T/F: incidence oforopharyngeal squamous cell carcinoma (OPSCC) is increasing
true
is there nodal involvement with oral squamous cell carcinoma (OSCC)?
yes
is there nodal involvement with oropharyngeal squamous cell carcinoma (OPSCC)?
yes and may be the only sign of the disease
gender predilection for oral squamous cell carcinoma (OSCC)
3 M: 1 F
gender predilection for oropharyngeal squamous cell carcinoma (OPSCC)
5 M : 1 F
what percent of pts with oral squamous cell carcinoma (OSCC) were smokers?
80-90%
what percent of pts with oropharyngeal squamous cell carcinoma (OPSCC) were smokers?
50-65%
does ETOH have a synergistic effect on pts with oral squamous cell carcinoma (OSCC)?
yes
does ETOH have a synergistic effect on pts with oropharyngeal squamous cell carcinoma (OPSCC)?
no, not significant factor
what is the px of oral squamous cell carcinoma (OSCC)?
40% survival rate
what is the px of oropharyngeal squamous cell carcinoma (OPSCC)?
80% survival rate
T/F: oropharyngeal squamous cell carcinoma (OPSCC) can be HPV+ or HPV-
true