Benign Mesenchymal Tumors - part I Flashcards
tissue of mesoderm origin
- fibrous
- adipose
- nerve
- blood
- lymph
- muscle
fibrous benign mesenchymal tumors
- fibroma
- inflammatory fibrous hyperplasia
- inflammatory papillary hyperplasia
- pyogenic granuloma
- peripheral giant cell granuloma
- peripheral ossifying fibroma
what causes fibroma (irritation fibroma)?
collagen deposition secondary to trauma
T/F: true fibromas are neoplasms, but controversy as to whether irritation fibromas are
true
what are considered fibromas?
- frenal tag
2. retrocuspid papilla
where does fibromas affect?
buccal mucosa and tongue (but potentially any mucosal surface)
clinical features of fibroma
- smooth or slightly papillary surface
- dome-shaped
- sessile or pedunculated
- most 1.5 cm or less
- may ulcerate if traumatized
- asymptomatic unless traumatized
frental tag
small, innocuous growth easily diagnosed clinically
tx for frenal tag
none necessary
retrocuspid papilla
bilateral papular lesions on the gingiva lingual to the mandibular canines
histopathologic features of fibroma
nodular mass of dense fibrous CT
tx of fibroma
conservative excision
T/F: recurrence of fibroma is rare
true
what is inflammatory fibrous hyperplasia (IFH) also known as?
- denture epulis
- epulis fissuratum
- denture-induced fibrous hyperplasia
clinical features of IFH
- flange of ill-fitting denture
2. may have central fissure/ulcer
histopathologic features of IFH
fibrovascular CT covered by stratified squamous epithelium
tx of IFH
- conservative excision
2. remake denture
prognosis of IFH
excellent if appropriately treated
what is inflammatory papillary hyperplasia (IPH) also known as?
denture papillomatosis - may have superficial candidiasis
what causes IPH?
- ill-fitting maxillary denture
- poor denture hygiene
- wearing denture 24/7
clinical features of IPH
- numerous asymptomatic red/erythematous papules
2. central region of hard palatal mucosa
IPH affects the central region of hard palatal mucosa due to what?
- maxillary denture
- high palatal vault
- habitual mouth breathers
histopathologic features of IPH
- papillary surface
2. edema (accumulation of fluid in the extracellular spaces of a tissue)
tx of IPH
- topical or systemic antifungal therapy
- removal of the denture may allow the erythema and edema to subside
- excise hyperplastic tissue before fabricating a new denture
prognosis of IPH
good after tx if pt keeps denture out and keeps it clean
reactive lesion
exuberant response to local irritation or trauma (hyperplastic granulation tissue)
T/F: pyogenic granuloma is a reactive lesion
true
when does pyogenic granuloma frequently occur?
during pregnancy “pregnancy tumor”
T/F: pyogenic granuloma is neither “pyogenic” nor a “granuloma”
true
T/F: pyogenic granuloma is unrelated to an infection
true
T/F: pyogenic granuloma is not a true granuloma
true
clinical features of pyogenic granuloma
- rapid growth
- painless
- red
- often ulcerated
- any body surface
- bleeds easily
what are the most common intraoral sites for pyogenic granuloma?
gingiva
what are the intraoral sites for pyogenic granuloma?
- gingiva
- lips
- tongue
if something is growing out of a socket, what are the 3 options?
- epulis granulomatosa
- lymphoma
- metastatic disease
what is epulis granulomatosa also known as?
liver clot
histopathologic features of pyogenic granuloma
vascular granulation tissue
vascular granulation tissue histopathologically
proliferation of fibroblasts and new thin-walled capillaries and inflammatory cells (plasma cells, lymphocytes) in a loose extracellular matrix
tx of pyogenic granuloma
excise, remove irritants
T/F: pyogenic granuloma recurs
true (15% recur)
T/F: peripheral giant cell granuloma is a reactive lesion
true
clinical features of peripheral giant cell granuloma
- painless
2. dusky purple-red
where does peripheral giant cell granuloma only affect?
only on gingiva of alveolar ridge, including edentulous ridge
radiographic features of peripheral giant cell granuloma
cupping of underlying bone sometimes is seen
histopathologic features of peripheral giant cell granuloma
granulation tissue with numerous benign multinucleated giant cells
tx of peripheral giant cell granuloma
excise, remove irritants
T/F: peripheral giant cell granuloma will recur
true, 15% recur
T/F: peripheral ossifying fibroma is a reactive lesion
true
clinical features of peripheral ossifying fibroma
- painless
- firm
- coral-pink
- may be ulcerated
where does peripheral ossifying fibroma occur?
found only on the gingiva
histopathologic features of peripheral ossifying fibroma
- cellular fibrous CT
2. variable amounts of calcification
tx of peripheral ossifying fibroma
excise, remove irritants
T/F: peripheral ossifying fibroma recurs
true, 15% recur
which fibrous lesions are “bumps on the gums”?
“3 P’s”
- pyogenic granuloma
- peripheral giant cell granuloma
- peripheral ossifying fibroma