Bone Neoplasms - part I Flashcards
benign neoplasms of bone
- central ossifying fibroma
- osteoma
- central giant cell granuloma
malignant neoplasms of bone
- chondrosarcoma
- osteosarcoma
- metastatic disease
what is central ossifying fibroma confused with in the past?
focal COD
T/F: most authorities consider central ossifying fibroma to be an osteogenic neoplasm
true
T/F: central ossifying fibroma is common
false, rare
who is affected by central ossifying fibroma?
adult (3rd-4th decade)
T/F: central ossifying fibroma has a female predilection
true
where does central ossifying fibroma primarily affect?
mandibular molar/pre-molar region
T/F: central ossifying fibroma can be asymptomatic esp when small
true
clinical features of central ossifying fibroma
- may see jaw expansion
2. facial asymmetry to significant deformity
radiographic features of central ossifying fibroma
- usually unilocular, occasionally multilocular
2. well-circumscribed with varying amount of central opacity
what is the range of radiolucency for central ossifying fibroma?
range from almost completely radiolucent to radiodense with a defined lucent border
what does central ossifying fibroma resemble radiographically?
focal COD
histopathologic features of central ossifying fibroma
- fibrous tissue with variable mixture of bony trabeculae and cementum-like material
- microscopically similar to fibrous dysplasia
what is needed for the correlation of fibrous dysplasia and central ossifying fibroma?
need radiograph
tx of central ossifying fibroma
enucleation - lesion tends to shell out as one mass
prognosis of central ossifying fibroma
excellent
T/F: recurrence of central ossifying fibroma is common
false, uncommon
what can central ossifying fibroma cause?
hyperparathyroid-jaw tumor syndrome
hyperparathyroid-jaw tumor syndrome
- multiple jaw lesions
2. hyperparathyroidism –> hypercalcemia
hyperparathyroid-jaw tumor syndrome lesions are histopathologically consistent with what?
central ossifying fibroma
hyperparathyroid-jaw tumor syndrome increases one’s risk for development of what?
parathyroid carcinoma
what is NOT considered osteoma?
- palatal tori
- mandibular tori
- buccal exostoses
T/F: although palatala tori, mandibular tori and buccal exostoses are not considered osteomas, they are all histopathologically identical
true