Bone Neoplasms - part I Flashcards
benign neoplasms of bone
- central ossifying fibroma
- osteoma
- central giant cell granuloma
malignant neoplasms of bone
- chondrosarcoma
- osteosarcoma
- metastatic disease
what is central ossifying fibroma confused with in the past?
focal COD
T/F: most authorities consider central ossifying fibroma to be an osteogenic neoplasm
true
T/F: central ossifying fibroma is common
false, rare
who is affected by central ossifying fibroma?
adult (3rd-4th decade)
T/F: central ossifying fibroma has a female predilection
true
where does central ossifying fibroma primarily affect?
mandibular molar/pre-molar region
T/F: central ossifying fibroma can be asymptomatic esp when small
true
clinical features of central ossifying fibroma
- may see jaw expansion
2. facial asymmetry to significant deformity
radiographic features of central ossifying fibroma
- usually unilocular, occasionally multilocular
2. well-circumscribed with varying amount of central opacity
what is the range of radiolucency for central ossifying fibroma?
range from almost completely radiolucent to radiodense with a defined lucent border
what does central ossifying fibroma resemble radiographically?
focal COD
histopathologic features of central ossifying fibroma
- fibrous tissue with variable mixture of bony trabeculae and cementum-like material
- microscopically similar to fibrous dysplasia
what is needed for the correlation of fibrous dysplasia and central ossifying fibroma?
need radiograph
tx of central ossifying fibroma
enucleation - lesion tends to shell out as one mass
prognosis of central ossifying fibroma
excellent
T/F: recurrence of central ossifying fibroma is common
false, uncommon
what can central ossifying fibroma cause?
hyperparathyroid-jaw tumor syndrome
hyperparathyroid-jaw tumor syndrome
- multiple jaw lesions
2. hyperparathyroidism –> hypercalcemia
hyperparathyroid-jaw tumor syndrome lesions are histopathologically consistent with what?
central ossifying fibroma
hyperparathyroid-jaw tumor syndrome increases one’s risk for development of what?
parathyroid carcinoma
what is NOT considered osteoma?
- palatal tori
- mandibular tori
- buccal exostoses
T/F: although palatala tori, mandibular tori and buccal exostoses are not considered osteomas, they are all histopathologically identical
true
what is osteoma composed of?
compact or cancellous bone
what is osteoma confirmed by?
continuous growth
who is affected by osteoma?
adult
clinical features of osteoma
- usually painless, but pain/swelling possible
2. slow growing
where may osteoma arise?
on bone surface or within bone (exostosis/enostosis)
T/F: gnathic lesions are more common than paranasal sinus involvement in osteoma
false, paranasal sinus involvement more common
where does gnathic osteoma lesions most commonly found?
- mandibular body
- condyle
- inferior border of angle
- coronoid process
- ramus
osteomas on body of mandible is often found where?
lingual premolar/molar area
what might condylar involvement for osteoma cause?
- limit mouth opening
- cause malocclusion
- deviation of midline
- chin to unaffected side
radiographic features of osteoma
circumscribed radiopaque mass
how might periosteal (exostoses) osteoma appear on radiographs?
may be uniformly sclerotic or have central trabeculations
how might endosteal (endostoses) appear on radiographs?
may appear similar/identical to idiopathic osteosclerosis or condensing osteitis
histopathologic features of osteoma
dense bone, minimal marrow or trabeculae and fibrofatty marrow
tx of small, asymptomatic osteoma
none, observe