Bone Neoplasms - part II Flashcards
malignant neoplasms of bone
- chondrosarcoma
- osteosarcoma
- metastatic disease
chondrosarcoma
malignancy of cartilaginous differentiation
T/F: chondrosarcoma is common
false, rare
what is the 2nd most common PRIMARY bone malignancy?
chondrosarcoma
who is affected by chondrosarcoma?
mostly adult males, 4th-6th decade
where does chondrosarcoma most commonly affect?
- femur
- pelvis
- ribs
T/F: teeth involved with chondrosarcoma test nonvital
false, VITAL
in what way might chondrosarcoma mimic dental infection?
- ± pain
- swelling
- loose teeth
radiographic features of chondrosarcoma
- poorly defined radiolucency with variable amounts of radiopacity
- may see widened PDL in area of tumor
- loss of lamina dura
T/F: larger chondrosarcoma lesions may appear unilocular
false, multilocular
histopathologic features of chondrosarcoma
invasive lobules of atypical cells showing cartilaginous differentiation
- hypercellular
- binucleation variation size/shape
- mitoses
- eggshell like chamber with vacuolar space holding chondrocyte
tx for chondrosarcoma
radical surgery “one chance for cure”
prognosis of chondrosarcoma depends on what?
- location
2. histopathologic grade of tumor
prognosis of chondrosarcoma
poor
death from chondrosarcoma is usually by what?
direct extension of tumor involving vital structures
where does chondrosarcoma often metastasize?
lung
T/F: osteosarcoma is uncommon
true
what is the most common PRIMARY bone malignancy?
osteosarcoma
skeletal distribution of osteosarcoma
- 8% jaws
- 10% humerus
- 15% hips/proximal femur
- 60% distal femur/knees
T/F: pain is often initial complaint in long bones and jaws in osteosarcoma pts
true
clinical features of osteosarcoma in jaws
- swelling
- loose teeth
- paresthesia
radiographic features of osteosarcoma
- mixed radiolucent/radiopaque with ill-defined borders
2. symmetrically widened PDL of teeth in area