Hospital Antibiotic Man

Question 1

Mild/moderate community acquired pneumonia (CURB 0-2).

Answer 1

Amoxicillin (5 days)

Doxycycline if pen allergic

Question 2

Severe CAP (CURB 3-5)

Answer 2

Co-amoxiclav IV and doxycycline PO

Question 3

Non-severe hospital acquired pneumonia

Answer 3

Amoxicillin PO

Doxycycline if penicillin allergic

Question 4

Severe HAP.

Answer 4

IV amoxicillin and gentamicin

Step down co-trimoxazole

Question 5

Aspiration pneumonia

Answer 5

Non-severe: amox and met

Severe: amox, met and gent

Question 6

Acute COPD exacerbation

Answer 6

Amoxicillin 1st line

Doxycycline 2nd line

Question 7

Native valve subacute endocarditis

Answer 7

Amoxicillin and gentamicin IV

Question 8

Native valve acute endocarditis (severe sepsis)

Answer 8

Flucloxacillin IV

Question 9

Prosthetic valve or suspected MRSA

Answer 9

Vancomycin and gentamicin IV and rifampicin PO

Question 10

C. diff infection

Answer 10

Non-severe: PO metronidazole

Severe - PO vancomycin and maybe IV metronidazole

Question 11

Peritonitis/biliary tract/intra-abdominal sepsis

Answer 11

IV amox, met and gent
Step down co-trimoxazole and metronidazole
If pen allergic: IV vancomycin, metronidazole and gentamicin

Question 12

Spontaneous bacterial peritonitis

Answer 12

Mild: co-trimoxazole

Severe disease: piperacillin/tazobactam

Question 13

Complicated UTI/pyelonephritis/urosepsis

Answer 13

IV amoxicillin and gentamicin
Co-trim and gentamicin if pen allergic
Step down is co-trim
7 days

Question 14

Uncomplicated female lower UTI

Answer 14

Nitrofurantoin or trimethoprim 3 days

Question 15

Uncatheterised male UTI

Answer 15

Nitrofurantoin or trimethoprim 7 days

Question 16

Cellulitis

Answer 16

Flucloxacillin PO

Question 17

Open fracture prophylaxis

Answer 17

IV co-amoxiclav