Hospital Acquired Infection

Question 1

What types of bacteria is C Diff

Answer 1

Gram positive spore forming anaerobe

Question 2

What toxins do C. Diff produce and what symptoms do they cause

Answer 2

C. difficile produces toxins A and B

– Diarrhoea, Pseudomembranous colitis., which can cause dehydration and perforation

Question 3

What population does C. diff mainly affect

Answer 3

– older
– debilitated
– antibiotic-treated

Question 4

What new antibiotic can be used to treat C. diff

Answer 4

Fidaxomicin

Question 5

Non drug approach to treating C. diff

Answer 5

Faecal transfer

Question 6

What antlobtics predispose patients to c diff infections

Answer 6

Clindamycin (often used in penicillin allergic patients with cellulitis), cephalosporins,
ciprofloxacin

Question 7

Risk factor for UTI ?

Answer 7

Catheter

Question 8

What antibiotics does does E. coli demonstrate resistance to

Answer 8

Extended spectrum beta-lactamases

Question 9

Name some common UTI organisms

Answer 9

E.coli, Klebsiella, Proteus, Pseudomonas, Enterobacter

Question 10

Causative organisms of SSI

Answer 10

Staph aureus, MRSA, Coagulase-negative Staphylococcus

Question 11

Causative organisms of bacteraemia

Answer 11

Methicillin-resistant Staphylococcus aureus, coag –ve staph, E.Coli