Homeostasis Flashcards

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1
Q

% of ECF is ISF?

A

80%

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2
Q

% of ECF that is plasma?

A

20%

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3
Q

What happens if capillary perfusion fails and plasma proteins enter the tissue?

A

Gangrene

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4
Q

What ratio of TBW is ECF?

A

1/3

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5
Q

What ratio of TBW is ICF?

A

2/3

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6
Q

Why do females have less TBW on average?

A
  • Higher proportion of body fat
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7
Q

What % of muscle is water?

A

70%

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8
Q

What percentage of fat is water?

A

10%

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9
Q

Define homeostasis?

A

The body’s ability to maintain a constant internal environment

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10
Q

What is the process negative feedback control?

A
  • Change detected as a stimulus by a receptor
  • Information sent to an integrating centre
  • Integrating centre compares the stimulus to a reference level
  • Magnitude of difference sent to an effector as an ERROR signal
  • Effector responds equally opposite to fix
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11
Q

Feedforward control?

A
  • Body “predicts” a change before it happens

- Pre-emptive

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12
Q

Positive feedback?

A
  • Initial change from reference leads to even greater disturbance
  • Think like exponentials
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13
Q

What is the dilution principle?

A

c=m/v

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14
Q

What does the dilution principle allow you to calculate in the body?

A

Volume of distribution

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15
Q

What must be taken into account before using the dilution principle?

A
  • Volume that has been excreted
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16
Q

What 3 water compartments can be measured DIRECTLY?

A
  • Plasma
  • ECF
  • TBW
17
Q

How do you measure plasma?

A

Attach radioactive labels to plasma proteins

18
Q

Why is plasma volume able to be measured this way?

A

Plasma proteins can’t move out of the plasma

19
Q

What radioactive dye could you use?

A

Evans blue

20
Q

What do you use to measure ECF?

A

Sucrose

21
Q

What do you use to calculate TBW?

A

Radioactive water