HLA subtypes associated with diseases Flashcards
1
Q
A3
A
Hemochromatosis
2
Q
B8
A
Addison disease (&DR3/4) Myasthenia gravis
3
Q
B27
A
Psoriatic arthritis
Ankylosing spondylitis
IBD-associated arthritis
Reactive arthritis (formerly Reiter syndrome)
- PAIR
- Also known as seronegative arthropathies
4
Q
DQ2/DQ8
A
Celiac disease
5
Q
DR2
A
Multiple sclerosis
hay fever
SLE
Goodpasture syndrome
6
Q
DR3
A
Diabetes mellitus type 1 (&DR4) SLE (&DR2) Graves disease Hashimoto thyroiditis (&DR5) Addison disease (&DR4/B8)
7
Q
DR4
A
Rheumatoid arthritis diabetes mellitus type 1 (&DR3) Addison disease (&DR3/B8)
8
Q
DR5
A
Pernicious anemia-->vitamin B12 deficiency Hashimoto thyroiditis (&DR3)