Cell surface proteins Flashcards
1
Q
T cells
A
- TCR (binds antigen-MHC complex)
- CD3 (associated with TCR for signal transduction)
- CD28 (binds B7 on APC)
- CXCR4/CCR5 (co-receptors for HIV)
2
Q
Helper T cells
A
- CD4
* CD40L
3
Q
Cytotoxic T cells
A
- CD8
* CXCR4/CCR5
4
Q
B cells
A
- Ig (binds antigen)
- CD19, CD20, CD21 (receptor for EBV)
- CD40
- MHC II
- B7
5
Q
Macrophages
A
- CD14 (receptor for PAMPs, eg, LPS)
- CD40
- CCR5
- MHC II
- B7 (CD80/86)
- Fc and C3b receptors (enhanced phagocytosis)
6
Q
NK cells
A
*CD16 (binds Fc of IgG)
**CD56 (unique marker
for NK)
7
Q
Hematopoietic stem cells
A
*CD34
