HIV Medications Exam 1 Flashcards
1
Q
What are the classes of medications?
A
- Post-Attachment Inhibitors
- CCR5 Receptor Antagonist
- Fusion Inhibitor
- Nucleoside Reverse Transcriptase Inhibitors
- Non-nucleoside Reverse Transcriptase Inhibitors
- Integrase Inhibitors
- Protease Inhibitors
2
Q
Post-Attachment Inhibitors Agents
A
Ibalizumab
3
Q
CCR5 Receptor Antagonist Agents
A
Maraviroc
4
Q
Fusion Inhibitor Agents
A
Enfuvirtide
5
Q
Nucleoside Reverse Transcriptase Inhibitors Agents
A
- Lamivudine (C)
- Emtricitabine (C)
- Tenofovir disoproxil fumarate (A)
- Tenofovir alafenamide fumarate (A)
- Abacavir (G)
- Abacavir/lamivudine (Epzicom)
- Tenofovir DF /emtricitabine (Truvada)
- Tenofovir AF /emtricitabine (Descovy)
- Tenofovir DF /lamivudine (Cimduo)
6
Q
Non-nucleoside Reverse Transcriptase Inhibitors Agents
A
- Efavirenz
- Rilpivirine
- Doravirine
7
Q
Integrase Inhibitors Agents
A
- Raltegravir
- Elvitegravir
- Dolutegravir
- Bictegravir
8
Q
Protease Inhibitors Agents
A
- Atazanavir
* Darunavir
9
Q
Post-Attachment Inhibitors MOA
A
- Inhibits attachment of virus to CD4
- Attaches to second domain of CD4; changes the shape enough that the virus cannot attach to it but the normal functions for the body still works
10
Q
CCR5 Receptor Antagonist MOA
A
- Inhibits attachment of virus to CD4
* Sits on CCR5 receptor
11
Q
Fusion Inhibitor MOA
A
- Inhibits attachment of virus to CD4
* Attaches to gp41
12
Q
Nucleoside Reverse Transcriptase Inhibitors MOA
A
- Inhibits reverse transcription
- Look like nucleosides
- Nuc analogues that are incorporated into the transcription process but causes it to stop so it does not complete the protein
13
Q
Non-nucleoside Reverse Transcriptase Inhibitors MOA
A
- Inhibits reverse transcription
* Non-competitive inhibitor and binds to reverse transcriptase
14
Q
Integrase Inhibitors MOA
A
- Inhibits viral integration into host DNA
* Inhibits integrase enzyme
15
Q
Protease Inhibitors MOA
A
Inhibit protease enzyme and make the protein chain non-functional
